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Roekiah, c. 1941

Roekiah (1917–1945) was a kroncong singer and film actress from the Dutch East Indies. Born to two actors, she began her career at the age of seven, and by 1932 had become well-known in Batavia. Around this time she met her husband Kartolo. The two acted in the 1937 hit Terang Boelan, with Roekiah starring alongside Rd Mochtar; after the film's commercial success, Roekiah, Kartolo, and most of the cast and crew of Terang Boelan were signed to Tan's Film. They appeared in three films for the company, beginning with Fatima in 1938, before Mochtar left in 1940; his departure ended a partnership which had spawned numerous imitators. Mochtar's replacement, Djoemala, acted with Roekiah in four films, beginning with Sorga Ka Toedjoe, although these were less successful. During the peak of her career, Roekiah was a fashion and beauty icon, featuring in advertisements and drawing comparisons to Dorothy Lamour and Janet Gaynor. After the Japanese invaded the Indies in 1942, Roekiah took only one more film role before her death. Of her five children with Kartolo, one – Rachmat Kartolo – entered acting. Roekiah has often been cited as one of Indonesia's film pioneers. (Full article...)

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A sketch consisting only of the face and shirt collar. Across the nose, the cheeks adjacent to the nose and mouth, and the chin are numerous red pimples. Above are the words "1. Végétations vasculaires."

The history of tuberous sclerosis (TSC) research spans less than 200 years. Originally regarded as a rare pathological curiosity, TSC is now an important focus of research into tumour formation and suppression. The history of TSC research is commonly divided into four periods. In the late 19th century, notable physicians working in European teaching hospitals first described the cortical and dermatological manifestations (example pictured). At the start of the 20th century, these symptoms were recognised as belonging to a single medical condition. Further organ involvement was discovered, along with a realisation that the condition was highly variable in its severity. The late 20th century saw great improvements in cranial imaging techniques and the discovery of the two genes that cause TSC when mutations form on them: TSC1 and TSC2, which encode for the proteins hamartin and tuberin respectively. Finally, the start of the 21st century saw the beginning of a molecular understanding of the illness, along with possible non-surgical therapeutic treatments. (Full list...)

Hammer retroazimuthal projection

The Hammer retroazimuthal projection is a modified azimuthal proposed by Ernst Hermann Heinrich Hammer in 1910. As a retroazimuthal projection, azimuths (directions) are correct from any point to the designated center point. In whole-world presentation, the back and front hemispheres overlap, making the projection a surjective function. Here, the frontside and backside hemispheres, both with a 15° graticule and center point of 45°N, 90°W, are presented side-by-side.

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