User talk:Alfie66/Archive 1
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Archive 1 |
Inspiration
You have inspired me, consider your user page an inspiration. Thanks have a great day! eximo (talk) 03:56, 19 September 2009 (UTC)
FDA links
Hey - in response to your note at WT:MED about the FDA website reorganization, I've collated a list of all of the broken links to *.fda.gov from Wikipedia article-space. The list is at User:MastCell/FDA links. There are a lot, so it will probably take a team effort to fix them, but at least we have a list to work from. Feel free to jump in - just cross out any links you check and fix, so that we don't duplicate each others' work. MastCell Talk 00:06, 12 July 2009 (UTC)
- Wow, great. That helps a lot! -- Alfie±Talk 11:01, 12 July 2009 (UTC)
Thanks, and progress report
Thanks for your help with the broken links at User:MastCell/FDA links. I don't know whether WP:MED is on your watchlist, but I've posted a progress report there that may interest you. WhatamIdoing (talk) 17:52, 28 July 2009 (UTC)
- For sure WP:MED is on my watchlist, as are your FDA links. ;-)
I just posted a note about 301-errors. -- Alfie±Talk 12:01, 29 July 2009 (UTC)
WikiProject Cannabis
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You are invited to join WikiProject Cannabis, a WikiProject dedicated to improving articles related to Cannabis. You received this invitation because of your history editing articles related to the plant. The WikiProject Cannabis group discussion is here. If you are interested in joining, please visit the project page, and add your name to the list of participants. |
- Edit: Responding my post.
- No worries! Just thought I would send the invitation in case you are interested. I don't get involved in edit wars either. If you happen to change your mind, you are more than welcome to join in the future. Best wishes! --Another Believer (Talk) 15:47, 13 August 2009 (UTC)
- THX again. Maybe later on when we sorted things out at Medical cannabis. -- Alfie±Talk 15:52, 13 August 2009 (UTC)
- I understand. Please keep in mind that edit wars are uncommon and this is the first I have seen relating to a cannabis article since the project started. Actually, WP Cannabis is very new, so we are still in the process of trying to recruit constructive, active members. The invitation is always on the table. Take care! --Another Believer (Talk) 16:05, 13 August 2009 (UTC)
- Yeah, this is the first one I ever experienced myself also. Quite nasty. -- Alfie±Talk 16:12, 13 August 2009 (UTC)
- I understand. Please keep in mind that edit wars are uncommon and this is the first I have seen relating to a cannabis article since the project started. Actually, WP Cannabis is very new, so we are still in the process of trying to recruit constructive, active members. The invitation is always on the table. Take care! --Another Believer (Talk) 16:05, 13 August 2009 (UTC)
- THX again. Maybe later on when we sorted things out at Medical cannabis. -- Alfie±Talk 15:52, 13 August 2009 (UTC)
- You figured it out quickly. Please don't leave ridiculous messages on my talk page anymore. This is not a playground. 72.213.23.110 (talk) 03:11, 17 August 2009 (UTC)
- Message above in response to this. —Alfie±Talk 11:18, 28 August 2009 (UTC)
- You figured it out quickly. Please don't leave ridiculous messages on my talk page anymore. This is not a playground. 72.213.23.110 (talk) 03:11, 17 August 2009 (UTC)
IUVIENNA
If freedom of speech is so important that you damge a universities reputation than why not freedom of speech to RESTORE the image of a university —Preceding unsigned comment added by 84.112.168.187 (talk) 22:19, 15 February 2010 (UTC)
- All (sic!) your contributions to International University Vienna were rated as vandalism by other editors. Meditate about the typographical and grammatical errors you managed to produce in the single sentence above. Not such a fine reputation. BTW, maybe you never read your own talk page; your current warning level is 4 (of 4 possible ones). If you continue vandalizing Wikipedia, you will be blocked from editing without further warnings. 18:20, 16 February 2010 (UTC)
Your input is needed
Regarding the research cited by User:Cyclonenim about cannabis and chronic liver disease, and whether the risk is real or significant. Please also feel free to comment on anything else in the discussion about "medical marijuana" found here. A professional opinion about the risk of liver damage from cannabis use would be helpful. There is a link to the research in the discussion, and a free text version of the study is online here. Thanks. Viriditas (talk) 23:11, 14 May 2010 (UTC)
- I've posted another study on the same page for your consideration. Your views are very much welcome on the subject. Regards, --—Cyclonenim | Chat 17:54, 15 May 2010 (UTC)
- Hi folks! I'll leave for a conference tomorrow (which runs until Thursday 20th) and don't have all my references in electronic form with me. Let's see what I can do. Cheers! 19:42, 15 May 2010 (UTC)
- Much appreciated, look forward to it. I suspect it'll be off the reference desk by then so I'll go ahead and copy the discussion to the talk of medical cannabis as you suggested. T'ra! Regards, --—Cyclonenim | Chat 23:01, 15 May 2010 (UTC)
- BTW do you know whether it's possible to move rather than copy this section? I would prefer not to loose the edit history. nugneH. 23:47, 15 May 2010 (UTC)
- An administrator can move pages, but since it's listed at the reference desk and we can't move the whole thing, I doubt that's possible. You might want to check at the help desk in case someone has a solution. Regards, --—Cyclonenim | Chat 01:33, 16 May 2010 (UTC)
- OK, checked it; isn't possible for sections of pages. I copied another left-over from the reference-desk's archive - hopefully keeping the right order. Qapla' 08:44, 16 May 2010 (UTC)
- Not to my knowledge, but my knowledge isn't exhaustive :) Regards, --—Cyclonenim | Chat 14:40, 16 May 2010 (UTC)
- OK, checked it; isn't possible for sections of pages. I copied another left-over from the reference-desk's archive - hopefully keeping the right order. Qapla' 08:44, 16 May 2010 (UTC)
- An administrator can move pages, but since it's listed at the reference desk and we can't move the whole thing, I doubt that's possible. You might want to check at the help desk in case someone has a solution. Regards, --—Cyclonenim | Chat 01:33, 16 May 2010 (UTC)
- BTW do you know whether it's possible to move rather than copy this section? I would prefer not to loose the edit history. nugneH. 23:47, 15 May 2010 (UTC)
- Much appreciated, look forward to it. I suspect it'll be off the reference desk by then so I'll go ahead and copy the discussion to the talk of medical cannabis as you suggested. T'ra! Regards, --—Cyclonenim | Chat 23:01, 15 May 2010 (UTC)
Reviewer permission
![](http://upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Wikipedia_Reviewer.svg/130px-Wikipedia_Reviewer.svg.png)
Hello. Your account has been granted the "reviewer" userright, allowing you to review other users' edits on certain flagged pages. Pending changes, also known as flagged protection, is currently undergoing a two-month trial scheduled to end 15 August 2010.
Reviewers can review edits made by users who are not autoconfirmed to articles placed under pending changes. Pending changes is applied to only a small number of articles, similarly to how semi-protection is applied but in a more controlled way for the trial. The list of articles with pending changes awaiting review is located at Special:OldReviewedPages.
For the guideline on reviewing, see Wikipedia:Reviewing. Being granted reviewer rights doesn't change how you can edit articles even with pending changes. The general help page on pending changes can be found here, and the general policy for the trial can be found here.
If you do not want this userright, you may ask any administrator to remove it for you at any time. HJ Mitchell | Penny for your thoughts? 20:54, 26 June 2010 (UTC)
Cannabinoids & Acetylcholine
I wonder if you would mind briefly responding to a question about how cannabinoids affect the acetylcholine system? My curiosity was prompted by these two quotations:
- "Cannabinoids inhibit the release of several neurotransmitters in the hippocampus, like acetylcholine, norepinephrine, and glutamate, resulting in a major decrease in neuronal activity in that region. This decrease in activity resembles a 'temporary hippocampal lesion.'" from http://wiki.riteme.site/wiki/Effects_of_cannabis#Neurological_effects.
- "Cannabinoids, depending on the dose, inhibit the transmission of neural signals through the basal ganglia and cerebellum." from http://wiki.riteme.site/wiki/Short-term_effects_of_cannabis#Neurological_effects , which also includes the previous passage.
As you may know, my understanding of pharmacology is very limited, just that of a mildly-informed layman, but I thought cannabis acted as an acetylcholinesterase inhibitor, which would tend to cause an increase in intra-synaptic availability of acetylcholine, yes? And that this higher level of acetylcholine would tend to up-regulate neuronal sensitivity and firing? Or is that a simplistic understanding; perhaps its affects differ in that way by brain region? ( The source cited to support the hippocampus statement, btw, is J.E. Joy, S. J. Watson, Jr., and J.A. Benson, Jr, (1999). Marijuana and Medicine: Assessing The Science Base. Washington D.C: National Academy of Sciences Press. ) I've tried to research this myself, via Medline, etc, but any brief comment you might have time to provide would be most helpful, I'm sure. Thanks in advance, Ohiostandard (talk) 23:32, 21 May 2010 (UTC)
- You are right, that if cannabis would act as an acetylcholinesterase inhibitor, ACh–levels would increase. But this is not the case; ACh–levels are down–regulated. See the reference you quoted, Domino 1981, Gessa et al. 1998, and Grotenhermen 2004. Another source (sorry, not online): EF Domino; Cannabinoids and the cholinergic system. in: Nahas G, Sutin KM, Harvey DJ, and S Agurell (eds): Marihuana and Medicine. Totowa, NJ, Humana Press, 223–6 (1999). Therefore the statement in the article seems to be justified. 12:52, 22 May 2010 (UTC)
- This dose-dependency is confusing to me, but a related puzzle seems to be offered concerning the synthetic cannabinoid WIN55,212-2. Perhaps the discrepancy arises because previous researchers were using such massive doses of WIN 55,212-2, e.g. 5 or 10 mg/kg versus 0.01 to 0.15 mg/kg, but please see Acquas et al. in "Cannabinoid CB1 receptor agonists increase rat cortical and hippocampal acetylcholine release in vivo" ( European Journal of Pharmacology 401 (2000) 179–185, free full-text, here). May I quote briefly from that paper's discussion section?
- The present study shows that low, intravenous doses of cannabinoids stimulate acetylcholine release in the prefrontal cortex and hippocampus. As our conditions are more likely to mimic those of cannabinoid exposure through smoke in humans than those utilized in previous studies where high doses of cannabinoids were given i.p. (Carta et al., 1998; Gessa et al., 1998a), it is suggested that the changes in acetylcholine release observed here might reflect the changes taking place in humans smoking cannabis derivatives (marijuana and hashish). If this argument is correct, one would predict that exposure to cannabis in humans is associated to an increase rather than a decrease in brain acetylcholine release.
- ( Emphais mine. ) Thanks for the generosity of your reply; no demand for further assistance trying to understand this, but I'd of course be grateful. Ohiostandard (talk) 19:14, 23 May 2010 (UTC)
- Btw, I did address that earlier business quite badly in the first place, obviously, both with respect to venue and more emphatically with regard to AGF, and I'm truly sorry for the annoyance that must have caused you. I should have said so long ago, but the thing devolved so quickly into high drama between myself and another user, and was so exacerbated by a third user's sock-puppet involvement, that I felt the need to just let it cool down for a good long while. I would like to politely and briefly discuss the original issue with you at some point, if you'd be willing, but doing so is very low on my list of priorities. I'd certainly prefer to finish this current topic, first, for example, assuming you do want to comment further when you have the time. In any case, I was wrong, and I apologize. Ohiostandard (talk) 03:14, 24 May 2010 (UTC)
collapsing "Discussion of dose-response relationships."
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I think I understand this a little better after learning a bit more about pharmacodynamics, the nature of the dose-response relationship and about the concept of the therapeutic window. As is mentioned in the dose-response article, "Endocrine disruptors have also been cited with producing one effect at high dose and a different effect at low doses." That may be true of phytocannabinoids too, as it appears to be of the synthetic, WIN 55,212-2. They might increase acetylcholine levels at the range of plasma concentrations likely to result from inhaling cannabis smoke, and ultimately decrease them with much higher doses, e.g. at (cannabinoid) concentrations hundreds to thousands of times higher and which may correspond to Gessa's findings and to those of many of the in vitro protocols and results that have been reported. Also, can you easily point me to any ref that documents the range of plasma concentrations for the more prominent cannabinoids that typically results from smoking and/or vaporizing and/or ingesting any given strain of cannabis? I suppose it's reasonable to assume that they're on the order of magnitude of those produced by Sativex and Marinol, whatever that may be? Sounds like a lazy question, I know, but 20 - 30 minutes of searching didn't bring me to anything that directly or concisely addresses even its simpler forms. I did see a paper that said THC concentrations in heavy cannabis users over a seven-day abstinence regimen range between 1 ng/mL and 5.5 ng/mL, but that wasn't exactly what I was looking for. Any other clarifications would be most welcome, too, of course. Cheers, Ohiostandard (talk) 21:28, 27 May 2010 (UTC)
That is a very substantial reply, thank you! I'm slow to respond, but I thought I'd better at least tell you that I haven't forgotten about my small project to check on and report the "doses" ( or "concentrations", for in vitro? ) that were used in the studies that are cited on page 53 of Marijuana and Medicine. Lately it seems very easy for me to find a reason to put off the fun stuff; something always seems more urgent. I will finish that, though ... even if I probably won't be able to translate the study protocols into probable plasma concentrations.
I've looked at the references you provided about plasma concentrations from smoking cannabis; thanks for including those. Those references, along with your own comments, have brought me to a much greater appreciation of the problems that arise in trying to determine whether the plasma concentrations that a given study's "dosing protocol" is likely to produce are in the range that's produced by simply smoking cannabis. I'm amazed and rather dismayed to learn that ( among other impediments ) the degree of variability between persons is so incredibly high. Do you think the results reported by Naef, et al. are reliable? ( You wrote, about those results: "There were two volunteers with a relative bioavailability of ~60%, but also one with only 3.7% and another one with even only 0.4%." ) I wonder whether any of the eight subjects might have had any other substances on-board, substances that might increase or decrease bioavailability? I'm just "thinking out loud" here, btw, because the results seem so extraordinary to me. I don't expect you to answer those questions.
Besides the three examples you provided above, I suppose you've also seen this 2008 study by Goullé, et al.? It reports rather similar results: "After smoking THC bioavailability averages 30%. With a 3.55% THC cigarette, a peak plasma level near 160 ng/mL occurs approximately 10 min after inhalation."
In contrast to that, however, I found the results from a study by Hunault, et al. interesting ... and confusing, too. If I understand their results correctly, they report serum mean maximal concentrations (Cmax) as high as 231.0 microg/L for THC when more potent cannabis was smoked. That's 231,000 nanograms/liter of serum. ( I know that you know this, of course. The conversion is for my own benefit when I read this again. ) Is it possible that so huge a difference is somehow due to the difference between serum and plasma? Since serum is plasma minus clotting proteins, I mean? I'm just speculating again; I have no expectation of a specific reply to this, truly.
I certainly "came to the right shop" for general guidance in this, though: the world's largest forum on bioavailability and bioequivalence, indeed! I looked at your site, and I am impressed. Of course I didn't understand most of what I read there, but ... well, I can at least say that I really liked the Szent-Györgyi quotation about the nature of discovery!
You wrote, above, "LOL – Schmirkenfiffer: How did you manage to come up with a name giving zero google-hits? BTW, the second part of the name for a native speaker of German sounds like kiffer, which means pothead." I didn't know that, but the correct name is "Schmirkenkiffer". The other was just a typing error. And since the first part of the name is an archaic form of the English word smirk, I suppose that Schmirkenkiffer must be a pothead with a stupid, offensive grin. I'm not surprised: I never liked him anyway. He never reports the cannabinoid plasma concentrations his study protocols generate! ;-) Best, – OhioStandard (talk) 15:34, 9 June 2010 (UTC)
Dear Ohiostandard! As promised some of my original research to satisfy our private interests. To assess dose proportionality I fitted literature data (peak concentrations) to the weighted power model Y=AxB, where Y is the pharmacokinetic response (here Cmax), x the administered dose, and A and B are the parameters of the model. If the exponent B equals 1, the model reduces to that of dose linearity (i.e., response doubles with a doubled dose). In order to deal with heteroscedasticity the model was weighted with w=1/x. Cmax is not the optimal metric to assess dose proportionality – AUC would be a much better choice. As said somewhere above values of Barnett at al. were measured by RIA and may be too high. The biggest drawback of the pooled analysis is the fact that data originate from different studies. Here is a plot of the fit. Not so bad. B is 0.6886 (coefficient of variation 14.8%; 95% confidence interval: 0.3136 – 1.0635). Within the dose range of 3.71 mg to 69.4 mg the increase is not proportional; however, since 1 is included in the confidence interval, this deviation is not statistical significant (at α 0.05). In other words, if we double the dose (+100%) the model predicts an increase of only ≈69% in Cmax. I checked also the residuals and Barnett's data do not qualify as a statistical outlier and therefore can't be removed. But since this no serious work I can do what I like, namely remove it anyhow. The fit gets better; B 0.7838 (CV 9.51%) with a tighter CI of 0.4797 – 1.0878 (plot upon request). Maturity is the capacity to endure uncertainty. – John Huston Finley
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see my revert comment ;) mabdul 16:27, 8 September 2010 (UTC)
- OK, I see. 16:29, 8 September 2010 (UTC)
Mondegreen
I reverted the comment you added to Mondegreen because listing often-misunderstood lyrics has proved to open the floodgates in that article, bit I must say that I was startled to learn that the the lyrics are "Split up on a dark sad night" - I would have bet a zillion bucks it was "Split up on the docks that night"! - DavidWBrooks (talk) 15:39, 9 September 2010 (UTC)
- Hi David! Interesting stuff over there. ;-) But I didn't even know the article; the edit was done by Arrivisto – not me. 15:55, 9 September 2010 (UTC)
- Oops ... guess I clicked the wrong "Talk" label. Well, at least both your usernames start with the same letter. - DavidWBrooks (talk) 16:13, 9 September 2010 (UTC)
Heya
Think I've fixed it, but I just finger-fumbled a rollback on Down Syndrome, and just wanted to explain that no harm was intended. Have a great day! --j⚛e deckertalk 16:52, 17 September 2010 (UTC)
- THX for the note – you were too fast with your self-revert to surprise me. ;-) 16:57, 17 September 2010 (UTC)
10 points
I was wondering exactly how fast someone would fix that. Props to you —Preceding unsigned comment added by 216.93.148.153 (talk) 18:26, 17 September 2010 (UTC)
- Moore's law? 1 minute 21 seconds. ;-) 18:32, 17 September 2010 (UTC)
Warning to IP:203.177.67.116
I saw your warning on this page: User talk:203.177.67.116 about the user's test edits on Kris Aquino. Since he's already been given two warnings before, both within today, and he is active at the moment, should we not give him/her a level 3 warning? TYelliot (talk) 18:53, 19 September 2010 (UTC)
- Hi, you are right. I must confess, that I could not find the correct template in Twinkle. 18:55, 19 September 2010 (UTC)
- It's all right. I've fixed it. TYelliot (talk) 18:58, 19 September 2010 (UTC)
- THX! 19:00, 19 September 2010 (UTC)
- It's all right. I've fixed it. TYelliot (talk) 18:58, 19 September 2010 (UTC)
Hi. As you recently commented in the straw poll regarding the ongoing usage and trial of Pending changes, this is to notify you that there is an interim straw poll with regard to keeping the tool switched on or switching it off while improvements are worked on and due for release on November 9, 2010. This new poll is only in regard to this issue and sets no precedent for any future usage. Your input on this issue is greatly appreciated. Off2riorob (talk) 23:26, 20 September 2010 (UTC)
Speedy deletion declined: Aeropolis 2001
Hello Alfie66. I am just letting you know that I declined the speedy deletion of Aeropolis 2001, a page you tagged for speedy deletion, because of the following concern: Not blatantly vandalism or a hoax. Thank you. Kimchi.sg (talk) 01:20, 11 October 2010 (UTC)
Avengers references
Hello, I have cited my references in the Avengers article, after I had, someone claimed it was vandilism, what is this about, please can you explain.81.111.127.132 (talk) 02:52, 7 November 2010 (UTC)
- Hi! I think we have clarified that in the meantime. Please see Wayne's talk page. 03:11, 7 November 2010 (UTC)
Response
Dear Alfie,
the reference that states that rebetiko developed in 60 etc has to be removed altogether. This is a book that is not from a native i.e. Greek author. To put it in simple terms that guy just doesn't know what he is talking about. I am Greek and rebetiko player for more than 20 years and I can tell you that rebbetiko does not exist after 50s. Then you may call it "arhontorebetiko" that mostly reflects music listened by middle classes. I would be happy to discuss with you in more detail if you wish.
For now take care and please revert my correction ;)
Cheers, billarasgr — Preceding unsigned comment added by Billarasgr (talk • contribs) 13:55, 14 January 2011 (UTC)
- Hi Billarasgr! Please try to keep discussions in one place. If someone posts on your talk page, answer there. I copypasted everything to Talk:Rebetiko#Recent_edits - please continue there, and don't forget to sign you edits. 14:37, 14 January 2011 (UTC)
Servus
Hey, how are the Vandals doing? :)) Yangula (talk) 21:33, 8 April 2011 (UTC)
- The only vandalist is you.all just look at once how without reason you deleted all the information about section Skyladiko — Preceding unsigned comment added by 79.167.247.126 (talk • contribs) 23:06, 8 April 2011 (UTC)
- Καληνύχτα! Well, Rebetiko was semi-protected for three days; quit over there. Zeibekiko still protected (for a week),... but this / these guy(s) is / are busy all around. 23:15, 8 April 2011 (UTC)
- Καλημέρα Άλφη, schau mal hierher: Wikipedia:Sockpuppet investigations/Plouton2-Yangula (talk) 03:47, 9 April 2011 (UTC)
- Guten Morgen; schöne Transliteration! ;-) Und hier... Irgendwie mühsam. 03:54, 9 April 2011 (UTC)
- Ich glaub das sind zwei-drei 14jährige die uns nur vers%$#ern wollen. Au jedem Fall sind Sie nict müde zu kriegen-Yangula (talk) 04:00, 9 April 2011 (UTC)
- Yep, don't feed the troll. Ich geh' jetzt 'mal schlafen. 04:03, 9 April 2011 (UTC)
) Godd afternoon!I ll try to talk polite all the other users You puted as vandalisms I think are Greek and wants the best too.They dont hide as Greek.2 I d like to explain u something when we talk about Greece we d like to talk to other people with the correct points I ll show how the things gone you can think that I am vandalist too sure know hahaha,but I just want to tell the truth that is so obvious. In greece the real zeibekiko is that in 9/8 http://youtube/z1cfln_sV44 and this zeibekiko know all around the world!! including the nightclubs of USA UK! etc. LOOK KNOW the turk zeubek has no commons with zeibekiko is THAT www.youtube.com/watch?v=KQkAgyeX7fA .(in the steps of Greek island Ballos! 2/4)and it represents a small community. Its very bad by speaking good and donate in wiki with their ways to say lies in all over wiki.And someone's user's contributions,you can notice it too I wont say the name are always: laiko greek again greek again and and again giving all that vice versa informations and in real want Turk all over the Greek music in articles zebekiko and most bad in greek music. Its a same people. — Preceding unsigned comment added by 79.167.53.251 (talk • contribs) 01:11, 10 April 2011 (UTC)
- Quite late afternoon! See WP:REF, WP:NPOV, and don't forget to
-- ~~~~ sign your posts
. THX. 04:03, 10 April 2011 (UTC)
Re: Your tools
Ah, good spot. All fixed now, I think. - Jarry1250 [Who? Discuss.] 08:53, 9 April 2011 (UTC)
- THX, Jarry – great tools! 13:13, 9 April 2011 (UTC)
- I have added them as "acceptable" fonts. More can be done, but could you check that they no longer generate errors for me? Thanks, - Jarry1250 [Who? Discuss.] 16:47, 10 April 2011 (UTC)
- Perfect! I've tested lists of
- two fonts; the first on meta:SVG fonts, the second one of the five generic fonts each (i.e., five tests) → OK
- two fonts; the first on meta, the second not → Warning
- three fonts; the first two on meta, the last generic → OK
- That's it; THX! 19:16, 10 April 2011 (UTC)
- Perfect! I've tested lists of
- I have added them as "acceptable" fonts. More can be done, but could you check that they no longer generate errors for me? Thanks, - Jarry1250 [Who? Discuss.] 16:47, 10 April 2011 (UTC)
re: Cenote
Please don't template the regulars, as you did on my talk page. I removed the unreferenced banner from the section on Cenote because the section had at least one reference, and thus the template was inapplicable. Steven Walling 21:04, 13 May 2011 (UTC)
- Hi Steven! Nice essay. I agree that the template was a quick-shot. But: Did your read the text in italics? “Only the first sentence is referenced (actually I added it myself). Everything else in this section is still not referenced. So why did you remove the template without giving an explanation in the edit line?” BTW, if I post at your talk page, I'll have it on my watchlist – try to keep discussions in one place. Regards. 21:35, 13 May 2011 (UTC)
Thanks for the Barnstar!
Hi Alfie66! Thanks for the Barnstar! I'm glad to know that I'm not the only person working on Medical cannabis who is pulling for appropriate citations. Thank you for your encouragement! --Tea with toast (talk) 22:50, 15 May 2011 (UTC)
- Hi Tea with Tost! You are welcome. I arrived at the article in August 2009 by chance and questioned "250 indications" (which were stated in the article at that time) – just to be attacked. On the other hand see a nice discussion about dose-response with Ohiostandard. He also guided me to WP:RANDY ("Experts are scum.")... Given all above I'm a little bit reluctant working on the article any more, essentially just reverting plain vandalism or nonsense. 08:57, 16 May 2011 (UTC)
Rebetiko
Hello, about edit warning between me and user:Phso2 you may take a look at this Rebetiko thanks --CanarianIsland (talk) 21:27, 29 February 2012 (UTC)
- Hi CanarianIsland! Yes I have seen the story going on the last two days. Maybe it’s a good idea to have a nice cup of tea, relax, and discuss the issue(s) at Talk:Rebetiko instead of reverting each other immediately. All the best. Alfie↑↓© 00:00, 1 March 2012 (UTC)
Non-helical nucleic acids
Hi, Alfie! I hope you're well.
- THX; leaving for a conference in Budapest tomorrow…
I thought of you, the other day, while communicating with a new user who has a theory that, if I understand its main point correctly, some nucleic acids, including DNA, aren't helical in vivo but exist in what's being called a "side-by-side" structure. The chap seems very bright, an M.D., Ph.D., it seems, but he's also been very reactionary, understandably, I think, to resistance to his theory, and rather too identified in his ego with being right about it. The article in question is Non-helical models of nucleic acid structure.
I came to notice the article when a point was raised at ANI about the user, who was then operating as Notahelix (talk · contribs). Viriditas and others advised him to change his user name, because he has a website of the same name, and he switched to Voice of 5-23 (talk · contribs). The talk pages for both are, well, let's say "interesting", as is the talk page for the article itself. I don't have the qualifications to be able to evaluate his theory, myself, or even really join in its discussion in any productive way, but I have been pretty active trying to explain our policies to him, & etc. Since I know you do have the qualifications to evaluate and discuss his theory, I thought you might be interested to have a look. Do so only if you're truly interested; I'm not asking for you to help unless you just have an interest. But I find it interesting for the only part of the story I'm qualified to understand: the social aspect is fascinating, imo.
If you do join in the article, though, I'd take it as a favour if you'd try to be kind to the new editor. He's been very ... well, "outspoken" would be a polite description, but he did work on the article for 2 months, also, and I think that deserves some consideration and respect. Cheers, --OhioStandard (talk) 19:38, 2 June 2012 (UTC)
- Wow, what a fertile culture medium (pun intended!) WP is (not at last what you call the social aspect). “X-ray crystallography gestapo”. ;-) After briefly browsing through the article I'm afraid that I would put it in the fringe science drawer. I appreciate the patience you and all the other experienced editors have shown in the article's and the author's talk pages and at ANI. This one is interesting. Christian [sic] implications of a non-helical structure are beyond my intellectual reach. BTW, see my father's quote at the end of this post. I can't promise to join – especially as a non-native speaker of English. I'm skeptic to be able to reply with appropriate sensitivity & politeness – especially keeping in mind the great job you already have done trying to help at the user's talk page. All the best, Alfie↑↓© 23:22, 2 June 2012 (UTC)
- "Fertile culture medium" is wonderful. So is the quotation from your father, although I must ask your pardon for mentioning them in the same breath. So his theory is rubbish? I expected so, but didn't know; as I said, I don't have the training to be able to evaluate the article. Re the "great job" you praise me for, I'm ambivalent. I stroked his vanity a little, intentionally, since a sense of injured pride and ego-identification with his theory seemed to be half the trouble, at least, and I tried to very politely explain how Wikipedia works to him.
- He is certainly an intelligent man, in one sense of the word "intelligent", but I have my doubts that I've done the encyclopaedia a service by the help I've given him. I think he would have been blocked by now if I'd kept away, and that would probably have been the best thing for the project. He'll be blocked eventually, I suppose, but now it will probably be a long, drama-filled process before that happens. Sometimes the application of kindness interferes with the upholding of more important values.
- I'm afraid I often forget that, in favour of a default tendency to help the underdog, as I documented in this brief thread. I was disappointed that no one seems to have clicked on the "really bad overturn accident" video, though, as I find it quite amusing, and because it was so fitting, relative to the subject of Sunset Strip Diaries. The book seems to be about a young woman's life as a "band follower" or "groupie" in the "heavy metal" rock-and-roll scene of the 1990s. I freely admit my sense of humour is warped, however... also, if you do look at the video, perhaps the audio track might (?) be hard to follow, since the rate of speech is very fast.
- I hope you have a pleasant time in Budapest. Have some borscht for me; I love it, especially with some chewy, dark bread, that's still warm from the oven, and a stout beer. Heaven! I've sent you an e-mail, by the way. Cheers, --OhioStandard (talk) 05:57, 3 June 2012 (UTC)
- Hi OhioStandard! Well, I wouldn't call his theory rubbish, but outdated and of historical interest only. There's nothing bad as such – we also have an article on geocentric models. Problems would only arise if one would claim it to be an valid alternate theory to heliocentrism (or even a better one). Reminds me a little bit on the creation–evolution controversy. Antony–22 (talk⁄contribs) already started some chimney-sweeping and brought it to attention of WP:GEN.
- The video is wonderful; the audio is exceptional in its serious tone. Speed is not my problem. My audience is always surprised listening to me saying Heteroscedasticity in a few milliseconds.
- I think you are mixing somthing up. Borscht originates form the Ukraine – though most people (including myself) would place in Russia. Last week I had it in Moscow and – to my surprise – Austrian draught beer. Difficult to get in Hungary. Considering their post-communist history I would even expect to see only a few Russian restaurants in Budapest. But: Hungary = Goulash! Have to edit the article. Outside of Hungary goulash is associated with a stew-like dish, whereas in Hungary ordering gulyás you solely get a soup. If you want to get the stew, you have to order pörkölt. Confused?
- Approaching the Hungarian border; mobile net access too expensive to continue. Will answer your e-mail this evening (UTC). Cheers, Alfie↑↓© 12:43, 3 June 2012 (UTC)
- You have mail. ;-) Alfie↑↓© 17:12, 3 June 2012 (UTC)
Your revert of Dactarianou
Hello, please see my comment about your revert and warning at User talk:Dactarianou. Thanks, – Fut.Perf. ☼ 10:04, 18 June 2012 (UTC)
Category:Top 200 US Drugs of 2011 is undergoing deletion review
Thank you for your input on the WHO Model Lists of Essential Medicines. I'm notifying everybody who has been part of that discussion about a pending Categories for Discussion review regarding the newly created Category:Top 200 US Drugs of 2011. I've also put a notice on the project talk page here. Thanks again. - Stillwaterising (talk) 05:51, 7 October 2012 (UTC)
The Wikipedia Library now offering accounts from Cochrane Collaboration (sign up!)
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Cochrane Collaboration is an independent medical nonprofit organization consisting of over 28,000 volunteers in more than 100 countries. The collaboration was formed to organize medical scholarship in a systematic way in the interests of evidence-based research: the group conducts systematic reviews of randomized controlled trials of health-care interventions, which it then publishes in the Cochrane Library.
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Rollback at Slot canyon
Hi Alfie66! I noticed that you reverted my edits at Slot canyon adding two references without an edit summary; could you please explain your reasoning? Thanks! EpicPupper (talk) 16:22, 19 February 2023 (UTC)
- Hi Eric,
sorry, I was too fast. However, the references you added don’t support the sentence in the article “Australia's Blue Mountains in particular have claimed the lives of several often due to flash flooding.” Honestly, I’m tempted to delete the sentence sooner or later… The article is about Slot canyons, not the Blue Mountains. Alfie↑↓© 22:30, 19 February 2023 (UTC)
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