Jump to content

Uronate dehydrogenase

From Wikipedia, the free encyclopedia
uronate dehydrogenase
Identifiers
EC no.1.1.1.203
CAS no.37250-98-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, an uronate dehydrogenase (EC 1.1.1.203) is an enzyme that catalyzes the chemical reaction

D-galacturonate + NAD+ + H2O D-galactaro-1,5-lactone + NADH + H+

The 3 substrates of this enzyme are D-galacturonate, NAD+, and H2O, whereas its 3 products are D-galactaro-1,5-lactone (the lactone of D-galactarate), NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is uronate:NAD+ 1-oxidoreductase. Other names in common use include uronate: NAD-oxidoreductase, and uronic acid dehydrogenase.

References

[edit]
  • Kilgore WW, Starr MP (1959). "Uronate oxidation by phytopathogenic pseudomonads". Nature. 183 (4672): 1412–3. Bibcode:1959Natur.183.1412K. doi:10.1038/1831412a0. PMID 13657147. S2CID 4256355.