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Uracil dehydrogenase

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Uracil dehydrogenase
Identifiers
EC no.1.1.99.19
CAS no.9029-00-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Uracil dehydrogenase (EC 1.1.99.19, uracil oxidase) is an enzyme with systematic name uracil:(acceptor) oxidoreductase.[1] This enzyme catalyses the following chemical reaction

uracil + acceptor barbiturate + reduced acceptor

Also oxidizes thymine. The enzyme acts on the hydrated derivative of the substrate.

References

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  1. ^ Hayaishi O, Kornberg A (May 1952). "Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes". The Journal of Biological Chemistry. 197 (2): 717–32. PMID 12981104.
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