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Streptomonospora alba

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Streptomonospora alba
Scientific classification
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Streptomonospora alba

Li et al. 2003

Streptomonospora alba is a halophilic species of bacteria.[1] YIM 90003(T) (=CCTCC AA001013(T)=DSM 44588(T)) is the type strain. It is closest to Streptomonospora salina. Its genome sequence was reported in 2015.[2]

Description

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Its aerial mycelium and substrate mycelium are well developed on most media. The aerial mycelium form short spore chains, bearing non-motile, straight to flexuous spores with wrinkled surfaces.

Metabolites

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Streptomonospora alba was found to produce streptomonomicin, a lasso peptide antibiotic.[2] Streptomonomicin displayed selective antibacterial activity against bacteria of the Bacillota phylum, especially Bacillus anthracis, while being inactive against Pseudomonadota or Ascomycota.

References

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  1. ^ Li WJ, Xu P, Zhang LP, et al. (September 2003). "Streptomonospora alba sp. nov., a novel halophilic actinomycete, and emended description of the genus Streptomonospora Cui et al. 2001". International Journal of Systematic and Evolutionary Microbiology. 53 (Pt 5): 1421–5. doi:10.1099/ijs.0.02543-0. PMID 13130027. Retrieved 2013-07-24.
  2. ^ a b Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA (2015). "Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso peptide from an understudied halophilic actinomycete". Chemistry & Biology. 22 (2): 241–50. doi:10.1016/j.chembiol.2014.11.017. PMC 4336579. PMID 25601074.

Further reading

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  • Whitman, William B., et al., eds. Bergey's manual® of systematic bacteriology. Vol. 5. Springer, 2012.
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