SLC22A25

SLC22A25
Identifiers
Aliases	SLC22A25, HIMTP, UST6, solute carrier family 22 member 25
External IDs	OMIM: 610792; MGI: 2442750; HomoloGene: 77136; GeneCards: SLC22A25; OMA:SLC22A25 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	63,243,599 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	8,382,475 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; buccal mucosa cell; ; gonad; ; gallbladder; ; nucleus accumbens; ; vagina; ; white blood cell; ; myeloid leukocyte; ; monocyte; ; right frontal lobe;
	Top expressed in
	proximal tubule; ; right kidney; ; human kidney; ; liver; ; gallbladder; ; metanephros; ; embryo; ; primary oocyte; ; neural layer of retina; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	sodium-independent organic anion transmembrane transporter activity; inorganic anion exchanger activity; urate transmembrane transporter activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; plasma membrane;
Biological process	sodium-independent organic anion transport; transmembrane transport; inorganic anion transport; urate transport; organic anion transport;
	Sources:Amigo / QuickGO
Orthologs
	387601
	319800
	ENSG00000196600
	ENSMUSG00000052562
	Q6T423
	n/a
	NM_199352; NM_001394058; NM_001394059
	NM_177002
	NP_955384
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 22 member 25 (SLC22A25), also known as organic anion transporter UST6, is a protein that in humans is encoded by the SLC22A25 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196600 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052562 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: solute carrier family 22".
^ Jacobsson JA; Haitina T; Lindblom J; Fredriksson R (November 2007). "Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family". Genomics. 90 (5): 595–609. doi:10.1016/j.ygeno.2007.03.017. PMID 17714910.

Eraly SA; Monte JC; Nigam SK (2004). "Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters". Physiol. Genomics. 18 (1): 12–24. doi:10.1152/physiolgenomics.00014.2004. PMID 15054140. S2CID 11787759.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Zaïr ZM; Eloranta JJ; Stieger B; Kullak-Ublick GA (2008). "Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney" (PDF). Pharmacogenomics. 9 (5): 597–624. doi:10.2217/14622416.9.5.597. PMID 18466105.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196600 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000052562 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: solute carrier family 22".

[pmid17714910-6] Jacobsson JA; Haitina T; Lindblom J; Fredriksson R (November 2007). "Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family". Genomics. 90 (5): 595–609. doi:10.1016/j.ygeno.2007.03.017. PMID 17714910.

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References

Further reading