EC 4.1.1.102
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| phenacrylate decarboxylase | |||||||||
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| Identifiers | |||||||||
| EC no. | 4.1.1.102 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, a phenacrylate decarboxylase (EC 4.1.1.102) is an enzyme that catalyzes the chemical reaction
- 4-coumarate 4-vinylphenol + 2 CO2
Hence, this enzyme has one substrate, 4-coumarate, and two products, 4-vinylphenol and carbon dioxide.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-phenylprop-2-enoate carboxy-lyase. Other names in common use include ferulic acid decarboxylase, and phenolic acid decarboxylase. It employs a prenylated flavin cofactor.
References
[edit]- Mukai N, Masaki K, Fujii T, Kawamukai M, Iefuji H (2010). "PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae". J. Biosci. Bioeng. 171 (5): 564–9. doi:10.1016/j.jbiosc.2009.11.011. PMID 20471595.
- Peng M, Mittmann E, Wenger L, Hubbuch J, Engqvist M, Niemeyer C, Rabe K (2019). "3D-Printed Phenacrylate Decarboxylase Flow Reactors for the Chemoenzymatic Synthesis of 4-Hydroxystilbene". Chemistry – A European Journal. 25 (70): 15998–16001. doi:10.1002/chem.201904206. PMC 6972603. PMID 31618489.
