Jump to content

Carboxybiotin decarboxylase

From Wikipedia, the free encyclopedia
Carboxybiotin decarboxylase
Identifiers
EC no.7.2.4.1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Carboxybiotin decarboxylase (EC 7.2.4.1, MadB, carboxybiotin protein decarboxylase) is an enzyme with systematic name carboxybiotinyl-(protein) carboxy-lyase.[1][2] This enzyme catalyses the following chemical reaction

a carboxybiotinyl-[protein] + n Na+in + H+out CO2 + a biotinyl-[protein] + n Na+out (n = 1--2)

This enzyme is an integral membrane protein MadB from the anaerobic bacterium Malonomonas rubra.

Nomenclature

[edit]

This enzyme was previously classified as EC 4.3.99.2.

References

[edit]
  1. ^ Berg M, Hilbi H, Dimroth P (April 1997). "Sequence of a gene cluster from Malonomonas rubra encoding components of the malonate decarboxylase Na+ pump and evidence for their function". European Journal of Biochemistry. 245 (1): 103–15. doi:10.1111/j.1432-1033.1997.00103.x. PMID 9128730.
  2. ^ Dimroth P, Hilbi H (July 1997). "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology. 25 (1): 3–10. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
[edit]