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Cadmium-transporting ATPase

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cadmium-transporting ATPase
Identifiers
EC no.7.2.2.2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
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NCBIproteins

In enzymology, a cadmium-transporting ATPase (EC 7.2.2.2) is an enzyme that catalyzes the chemical reaction

ATP + H2O ADP + phosphate

Thus, the two substrates of this enzyme are ATP and H2O, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (heavy-metal-exporting).

References

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  • Li ZS, Szczypka M, Lu YP, Thiele DJ, Rea PA (1996). "The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump". J. Biol. Chem. 271 (11): 6509–17. doi:10.1074/jbc.271.11.6509. PMID 8626454.
  • Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. PMID 9889977.