Apo-beta-carotenoid-14',13'-dioxygenase
Apo-beta-carotenoid-14',13'-dioxygenase (EC 1.13.11.67 is an enzyme that catalyzes the chemical reaction
- 8'-apo-beta-carotenol + O2 14'-apo-beta-carotenal + uncharacterized product
Thus, the two substrates of this enzyme are 8'-apo-beta-carotenol and oxygen, whereas its two products are 14'-apo-beta-carotenal and an uncharacterized product that may be (3E,5E)-7-hydroxy-6-methylhepta-3,5-dien-2-one.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is 8'-apo-beta-carotenol:O2 oxidoreductase.
References
[edit]- Daruwalla, A.; Zhang, J.; Lee, H. J.; Khadka, N.; Farquhar, E. R.; Shi, W.; von Lintig, J.; Kiser, P. D. (2020). "Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase". Proceedings of the National Academy of Sciences of the United States of America. 117 (33): 19914–19925. Bibcode:2020PNAS..11719914D. doi:10.1073/pnas.2004116117. PMC 7443882. PMID 32747548.
- Dmitrovskii AA, Gessler NN, Gomboeva SB (July 1997). "Enzymatic oxidation of beta-apo-8'-carotenol to beta-apo-14'-carotenal by an enzyme different from beta-carotene-15,15'-dioxygenase". Biochemistry. Biokhimiia. 62 (7): 787–92. PMID 9331970.