16-hydroxysteroid epimerase
Appearance
16-hydroxysteroid epimerase | |||||||||
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Identifiers | |||||||||
EC no. | 5.1.99.2 | ||||||||
CAS no. | 37318-40-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 16-hydroxysteroid epimerase (EC 5.1.99.2) is an enzyme that catalyzes the chemical reaction
- 16alpha-hydroxysteroid 16beta-hydroxysteroid
Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 16-hydroxysteroid 16-epimerase.
References
[edit]- Dahm K, Lindlau M, Breuer H (1968). "[Steroid epimerase--a new enzyme of estrogen metabolism]". Biochim. Biophys. Acta. 159 (2): 377–89. doi:10.1016/0005-2744(68)90086-7. PMID 5657462.