Zinc finger protein 208

ZNF208
Identifiers
Aliases	ZNF208, PMIDP, ZNF95, zinc finger protein 208
External IDs	OMIM: 603977; MGI: 1917477; HomoloGene: 133818; GeneCards: ZNF208; OMA:ZNF208 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	22,010,949 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	39,189,844 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; gonad; ; testicle; ; right auricle; ; left ventricle; ; apex of heart; ; anterior pituitary; ; left lobe of thyroid gland; ; islet of Langerhans; ; right testis;
	Top expressed in
	granulocyte; ; gastrula; ; genital tubercle; ; ventricular zone; ; otic vesicle; ; trigeminal ganglion; ; medial ganglionic eminence; ; tail of embryo; ; embryo; ; triceps brachii muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; zinc ion binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7757
	70227
	ENSG00000160321
	ENSMUSG00000068959
	O43345
	n/a
	NM_001329971; NM_001329972; NM_001329973; NM_001329974; NM_007153
	NM_001004139
	NP_001316900; NP_001316901; NP_001316902; NP_001316903; NP_009084
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 208 is a protein that in humans is encoded by the ZNF208 gene. ^[5]

Function

Zinc finger proteins (ZNFs), such as ZNF208, bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. A conserved protein motif, termed the Kruppel-associated box (KRAB) domain, mediates protein-protein interactions (Eichler et al., 1998 [PubMed 9724325]). See ZNF91 (MIM 603971) for further information on ZNFs.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000160321 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068959 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger protein 208". Retrieved 2016-01-28.

Function

References

Further reading