User:Vaughnm2020/Bone grafting
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[edit]Bone Xenografts
[edit]Bone xenografts are an alternative form of bone grafts that involve transplanting different animal species cells into humans[1]. This graft can range from orthopedic to dental uses. Most xenografts are derived from bovine sources such as cows or pigs and are sterilized and processed for safe implantation into human tissue. The success of these grafts furthers the accessibility of grafting in future medical studies.
Health Risks
[edit]Studies show that xenografts can be used, however they are closely monitored due to their risk of rejection. Zoonoses, which are diseases that arise from the crossing of animal and human tissue[2], pose a threat to the success of xenograft implantation. Specifically, these diseases are referenced as “xenozoonoses”. They can be categorized in 3 different groups: viral infection, prion-mediated infection, and bacterial infection[3]. They have the potential to create a public health risk if they are not closely monitored, as they can cause diseases to be more easily transmissible through different species.
References
[edit]- ^ Wellness, Anderson Periodontal (2021-02-25). "The Difference Between an Autograft, Allograft, and Xenograft". Anderson Periodontal Wellness. Retrieved 2023-04-09.
- ^ "Xenograft risks: What you and your patients need to know". www.aaos.org. Retrieved 2023-04-09.
- ^ Chong, Mark Seow Khoon; Bao, Chaolemeng; Ng, King Pan; Lim, Jing; Chan, Jerry Kok Yen (2016-09-01). "Human Bone Xenografts: from Preclinical Testing for Regenerative Medicine to Modeling of Diseases". Current Molecular Biology Reports. 2 (3): 158–170. doi:10.1007/s40610-016-0044-4. ISSN 2198-6428.