User:Vanessa R Garcia/Gene redundancy

*my changes in bold

Gene redundancy is the existence of multiple genes in the genome of an organism that perform the same function. Gene redundancy is the result of gene duplication. Such duplication events are responsible for many sets of paralogous genes (is this addressed in the first source?)^[1]. When an individual gene in such a set is disrupted by mutation or targeted knockout, there can be little effect on phenotype as a result of gene redundancy, whereas the effect is large for the knockout of a gene with only one copy.^[2]

^ Force, A; Lynch, M; Pickett, F B; Amores, A; Yan, Y L; Postlethwait, J (1999-04). "Preservation of duplicate genes by complementary, degenerative mutations". Genetics. 151 (4): 1531–1545. ISSN 0016-6731. PMC 1460548. PMID 10101175. {{cite journal}}: Check date values in: |date= (help)
^ Pérez-Pérez JM, Candela H, Micol JL (August 2009). "Understanding synergy in genetic interactions". Trends Genet. 25 (8): 368–76. doi:10.1016/j.tig.2009.06.004. PMID 19665253.

[1] Force, A; Lynch, M; Pickett, F B; Amores, A; Yan, Y L; Postlethwait, J (1999-04). "Preservation of duplicate genes by complementary, degenerative mutations". Genetics. 151 (4): 1531–1545. ISSN 0016-6731. PMC 1460548. PMID 10101175. {{cite journal}}: Check date values in: |date= (help)

[2] Pérez-Pérez JM, Candela H, Micol JL (August 2009). "Understanding synergy in genetic interactions". Trends Genet. 25 (8): 368–76. doi:10.1016/j.tig.2009.06.004. PMID 19665253.

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