User:TastyFungicide/Proflavin

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Article Draft

Lead

Proflavin is also used as a dye in vivo fluorescent imaging.^[1]

Article body

Proflavin is a fluorescent dye that is sometimes used in microscopic in-vivo imaging due to its intercalation properties. However, there was concern that women exposed to proflavin could develop cervical cancer since they have mutagenesis potential. However, the retrospective analysis performed by Pantano et. al. demonstrated that there is no increased cervical cancer risk after exposure to proflavin.^[1]

References

Pantano, N., Hunt, B., Schwarz, R.A., Parra, S., Cherry, K., Possati-Resende, J.C., Longatto-Filho, A., Fregnani, J.H.T.G., Castle, P.E., Schmeler, K. and Richards-Kortum, R. (2018), Is Proflavine Exposure Associated with Disease Progression in Women with Cervical Dysplasia? A Brief Report. Photochem Photobiol, 94: 1308-1313. https://doi.org/10.1111/php.12976

^ ^a ^b Pantano, Naitielle; Hunt, Brady; Schwarz, Richard A.; Parra, Sonia; Cherry, Katelin; Possati-Resende, Júlio César; Longatto-Filho, Adhemar; Fregnani, José Humberto Tavares Guerreiro; Castle, Philip E.; Schmeler, Kathleen; Richards-Kortum, Rebecca (2018-11). "Is Proflavine Exposure Associated with Disease Progression in Women with Cervical Dysplasia? A Brief Report". Photochemistry and Photobiology. 94 (6): 1308–1313. doi:10.1111/php.12976. PMC 6282608. PMID 29981148. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)

[:1-1] Pantano, Naitielle; Hunt, Brady; Schwarz, Richard A.; Parra, Sonia; Cherry, Katelin; Possati-Resende, Júlio César; Longatto-Filho, Adhemar; Fregnani, José Humberto Tavares Guerreiro; Castle, Philip E.; Schmeler, Kathleen; Richards-Kortum, Rebecca (2018-11). "Is Proflavine Exposure Associated with Disease Progression in Women with Cervical Dysplasia? A Brief Report". Photochemistry and Photobiology. 94 (6): 1308–1313. doi:10.1111/php.12976. PMC 6282608. PMID 29981148. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)

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