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Through the use of recombinant DNA technology, E.coli can be used for the production of human insulin. The biosynthesis of insulin within the human body confers a significant advantage over bovine or porcine synthesis, which are often immunogenic in diabetic patients^[1]

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^ Keefer, Linda M.; Piron, Marie-Agnes; De Meyts, Pierre (1981). "Human insulin prepared by recombinant DNA techniques and native human insulin interact identically with insulin receptors" (PDF). Proceedings of the National Academy of Sciences USA. 78: 1391–1395 – via NCBI.

[1] Keefer, Linda M.; Piron, Marie-Agnes; De Meyts, Pierre (1981). "Human insulin prepared by recombinant DNA techniques and native human insulin interact identically with insulin receptors" (PDF). Proceedings of the National Academy of Sciences USA. 78: 1391–1395 – via NCBI.

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