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Adverse effects[edit source | edit] Side effects, incidence differs depending on which disease state the patient is being treated for.[4]

Patients taking Lisinopril for the treatment of Hypertension may experience the following side effects:

Headache (3.8%) Dizziness (3.5%) Cough (2.5%) Difficulty swallowing or breathing (signs of angioedema), allergic reaction (anaphylaxis) Hyperkalemia (2.2% in adult clinical trials) Fatigue (1% or more) Steven-Johnson Syndrome (1% or more)

Patients taking Lisinopril for the treatment of Acute Myocardial Infarction may experience the following side effects:

Hypotension (5.3%) Renal Dysfunction (1.3%) Patients taking Lisinopril for the treatment of Heart Failure may experience the following side effects:

Hypotension (3.8%) Dizziness (12-19%) Chest pain (2.1%) Syncope (5-7%) Hyperkalemia (4.8% in adult clinical trials) Fatigue (1% or more) Steven-Johnson Syndrome (1% or more) Dark urine (melanuria)

Decreased urination (oliguria)

Hoarseness

Itching

Yellowing of skin or eyes (jaundice)

Abdominal pain, bloating, vomiting

Chest pain or tightness, dizziness, lightheadedness, fainting

Dry cough

Fever

Joint pain

Rash

Diarrhea, nausea

Drowsiness, headache, tiredness

Muscle cramps

Serious (possibly fatal) liver problems

Lisinopril causes the kidneys to retain potassium, which may lead to hyperkalemia. From a study on eHealthMe of more than 1,000 patients with hyperkalemia when using it, the condition may happen more in older male users.[5]

A rare but severe allergic reaction that affects the bowel wall and secondarily causes abdominal pain can occur. This "angioedema" reaction is very rare and must be given immediate medical attention.[6]