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User:Mr. Ibrahem/Warthin's tumor

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Warthin's tumor
Other namesPapillary cystadenoma lymphomatosum, Warthin tumour, monomorphic adenoma, adenolymphoma, cystadenolymphoma
This Warthin's tumor presented as a parotid mass in a middle-aged male, who underwent superficial parotidectomy. The tumor, at the right of the image, is well-demarcated from the adjacent parotid tissue and tends to shell out from it.
SpecialtyENT surgery
SymptomsRound, painless, slowly growing mass in the parotid gland[1]
ComplicationsFacial nerve palsy, cancer[1][2]
Usual onset60s and 70s[1]
TypesEpithelial predominance, mixed, lymphoid predominance[1]
CausesUnknown[1]
Risk factorsEpstein Barr virus, tobacco, autoimmune diseases, ionizing radiation, chronic inflammation[1]
Diagnostic methodBiopsy[2]
Differential diagnosisLymph node metastases, sebaceous lymphadenoma, cystadenoma[1]
TreatmentSurgery[1]
PrognosisGood[1]
Frequency2 to 15% of parotid tumors[1]

Warthin's tumor, also known as papillary cystadenoma lymphomatosum, is a non-cancerous tumor of the salivary glands.[1] It generally presents as a round, painless, and slowly growing mass.[1] It typically occurs in the parotid gland though may rarely occur in the mouth, nose, or eyelids.[1] Complications may include facial nerve palsy, and in less than 1% of cases it may become cancerous.[1][2]

The cause is unknown.[1] Risk factors may include Epstein Barr virus infection, tobacco, autoimmune diseases, ionizing radiation, and chronic inflammation.[1] Diagnosis is by tissue biopsy.[2]

Treatment is by surgical removal.[1] Warthin's tumor represents about 2% to 15% of parotid tumors.[1] It occurs most commonly in peoples 60s and 70s.[1] It was first described in 1895 by Hildebrand and was subsequently named after pathologist Aldred Scott Warthin, who described two cases in 1929.[1][3]

References

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  1. ^ a b c d e f g h i j k l m n o p q r s t Limaiem, F; Jain, P (January 2020). "Warthin Tumor". PMID 32491572. {{cite journal}}: Cite journal requires |journal= (help)
  2. ^ a b c d "Warthin tumor". rarediseases.info.nih.gov. Genetic and Rare Diseases Information Center (GARD) – an NCATS Program. Retrieved 13 February 2021.
  3. ^ Witt, Robert L., ed. (2005). "Chapter 9 "Benign tumors, cysts, and tumor-like conditions of the salivary glands". Salivary Gland Diseases: Surgical and Medical Management. New York: Thieme Medical Publishers. p. 123. ISBN 1-58890-414-8.