User:Mr. Ibrahem/Sufentanil
Clinical data | |
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Trade names | Dsuvia, Sufenta, Zalviso, others |
Other names | R30730 |
AHFS/Drugs.com | Monograph |
License data |
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Routes of administration | Intravenous therapy (IV), intramuscular injection (IM), subcutaneous injection (SQ), epidural, intrathecal |
Drug class | Opioid |
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Pharmacokinetic data | |
Elimination half-life | 162 minutes |
Duration of action | Up to 4 hr[1] |
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Chemical and physical data | |
Formula | C22H30N2O2S |
Molar mass | 386.55 g·mol−1 |
3D model (JSmol) | |
Melting point | 97 °C (207 °F) |
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Sufentanil, sold under the brand names Sufenta among others, is an opioid medication used to treat moderate to severe pain and during anesthesia.[1][2] It may be given under the tongue, by injection into a vein, or into epidural space.[1][2] Effects last for up to 4 hours.[1]
Common side effects include respiratory depression (insufficient breathing) and stiff muscles.[1] Other side effects may include abuse, adrenal insufficiency, low blood pressure, androgen deficiency, and serotonin syndrome.[1] It works by attaching to μ-opioid receptors in the brain.[2]
Sufentanil was first made in 174 and approved for medical use in the United States in 1984.[3][1] In the United States it costs about 50 USD for 500 ucg as of 2021.[4] In the United States it is classified as a Schedule II controlled substance.[1]
References
[edit]- ^ a b c d e f g h i j "SUFentanil Monograph for Professionals". Drugs.com. Archived from the original on 21 January 2021. Retrieved 15 October 2021.
- ^ a b c d "Dzuveo". Archived from the original on 23 November 2020. Retrieved 15 October 2021.
- ^ Baheti, Dwarkadas K.; Laheri, Vandana V. (31 March 2018). Understanding Anesthetic Equipment & Procedures: A Practical Approach. JP Medical Ltd. p. 16. ISBN 978-93-5270-316-6. Archived from the original on 17 October 2021. Retrieved 15 October 2021.
- ^ "Sufentanil Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 26 October 2020. Retrieved 15 October 2021.