User:MTLE4470 grp10 OF/sandbox
Functions
[edit]Resilin is a protein of Arthropod cuticle. Mainly, resilin is present in insect legs and wings joints, however, it may be in parts of proboscis[1]. The protein is involved in effective energy storage and has several functions. Resilin allows insects to increase efficacy of leg and wing work. Then, resilin location pattern influences the pattern of wing folding[2].
Applications
[edit]The properties of resilin became an object of interest for other fields. For example, in biomedical engineering, resilin was used to create resilin-like polypeptide (RLP) that have enhanced biological characteristics of resilin. RLPs were used to create new PEG hydrogel with facilitated photocrosslinking characteristics and compatibility with cells both in adhesion and mechanical properties[3]. RLPs are used in regenerative scaffolds for applications for cartilage (particularly, interbertebral discs[4]), muscles, vascular tissue, vocal fold regeneration[5]. Additionally, resilin can be combined with silk in a composite that obtains both remarkable elasticity of resilin and strength of silk[4]. Resilin also one of three materials that belong to biorubbers[6]. As biomimetic protein, resilin molecular properties were used in rec1-resilin and its conjugates with gold nanoparticles for novel research in biosensors[7].
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- ^ Krenn, Harald W. (2009-12-04). "Feeding Mechanisms of Adult Lepidoptera: Structure, Function, and Evolution of the Mouthparts". Annual Review of Entomology. 55 (1): 307–327. doi:10.1146/annurev-ento-112408-085338. PMC 4040413. PMID 19961330.
- ^ Haas, Fabian; Gorb, Stanislav; Blickhan, Reinhard (2000-07-22). "The function of resilin in beetle wings". Proceedings of the Royal Society of London B: Biological Sciences. 267 (1451): 1375–1381. doi:10.1098/rspb.2000.1153. ISSN 0962-8452. PMC 1690692. PMID 10983820.
- ^ McGann, Christopher L.; Dumm, Rebekah E.; Jurusik, Anna K.; Sidhu, Ishnoor; Kiick, Kristi L. (2017-01-25). "Thiol-ene Photocrosslinking of Cytocompatible Resilin-like Polypeptide-PEG Hydrogels". Macromolecular bioscience. 16 (1): 129–138. doi:10.1002/mabi.201500305. ISSN 1616-5187. PMC 4834209. PMID 26435299.
- ^ a b Whittaker, J. L.; Dutta, N. K.; Elvin, C. M.; Choudhury, N. R. (2015-08-05). "Fabrication of highly elastic resilin/silk fibroin based hydrogel by rapid photo-crosslinking reaction". J. Mater. Chem. B. 3 (32): 6576–6579. doi:10.1039/c5tb00970g. ISSN 2050-7518.
- ^ Li, Linqing; Tong, Zhixiang; Jia, Xinqiao; Kiick, Kristi L. (2012-12-13). "Resilin-like polypeptide hydrogels engineered for versatile biological function". Soft Matter. 9 (3): 665–673. doi:10.1039/c2sm26812d. ISSN 1744-6848.
- ^ R, Greenhalgh, Kerriann (2007-01-01). Development of biocompatible multi-drug conjugated nanoparticles/smart polymer films for biomedicinal applications (Thesis). University of South Florida.
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: CS1 maint: multiple names: authors list (link) - ^ Mayavan, Sundar; Dutta, Naba K.; Choudhury, Namita R.; Kim, Misook; Elvin, Christopher M.; Hill, Anita J. "Self-organization, interfacial interaction and photophysical properties of gold nanoparticle complexes derived from resilin-mimetic fluorescent protein rec1-resilin". Biomaterials. 32 (11): 2786–2796. doi:10.1016/j.biomaterials.2010.12.030.