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Bernard Roizman
NationalityAmerican
Scientific career
FieldsVirology, Herpes Simplex

Bernard Roizman is an American scientist. He is currently the Joseph Regenstein Distinguished Service Professor of Virology in the Departments of Molecular Genetics & Cell Biology, Biochemistry & Molecular Biology, and in Microbiology. of Biological Sciences, at the University of Chicago.


Education

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Bernard Roizman received his B.A. and M.S. from Temple University, Philadelphia, Pennsylvania and subsequently attended The Johns Hopkins University where he received his Sc.D.

Career

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Prof. Roizman is currently Joseph Regenstein Distinguished Service Professor of Virology in the Departments of Molecular Genetics & Cell Biology. He is also a faculty member in the Department of Biochemistry & Molecular Biology, and in Microbiology.

A virologist, he is considered to be the world's foremost expert on the herpes simplex virus.

Awards and Honors

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Pasteur Award, Illinois Society of Microbiology, 1972;
Esther Langer Award, 1974.
Honorary Fellow, Pan American Cancer Cytology Soc., 1973;
Elected: Member of the National Academy of Sciences, 1979;
Outstanding Alumnus in Public Health Award for 1984 Johns Hopkins Univ;
Centennial Medal, Institut Pasteur, Paris, France 1987;
First annual ICN International Prize in Virology, 1988;
Society of Scholars, The Johns Hopkins University, 1988;
Fellow, Japanese Soc. for the Promotion of Science, 1989;
Fellow, American Academy of Arts and Sciences, 1991;
Sesquicentennial Gold Medal, University of Ferrara, Italy, 1991;
Fellow, American Academy of Microbiology, 1992;
Recipient, Bristol Myers Squibb Unsolicited Research Grant Award in Infectious Diseases, 1991-1995;
Honorary Member, Hungarian Academy of Sciences, 1995;
J. Allyn Taylor International Prize in Medicine, 1997;
Bristol-Myers Squibb Award for Distinguished Achievement in Infectious Disease Research, 1998;
Foreign Member, Chinese Academy of Engineering, 2000;
Institute of Medicine, 2001;
NIH Outstanding Investigator Award 1988-2001;
Honorary member, Italian Soc. for Virology, 2002;
NIH-NCI Merit award, 2003;
Quantrell Award for Excellence in undergraduate teaching, 2003;
Fellow, American Association for the Advancement of Science, 2004;
Abbott-ASM Lifetime Achievement Award, 2008;


Honorary degrees:
Doctorate in Humane Letters, Governors State University, IL. 1984;
Doctorate in Medicine and Surgery. University of Ferrara, Italy 1991;
Doctorate in Science, University of Paris, France, 1997;
Doctorate in Medicine, Univ. of Valladolid, Spain, 2001;
Professor (honoris causa) Shandong Academy of Medical Sciences, China, 1985;
Peking Union Medical College, China, 2002;
Shandong Univ, 2003;
Qingdao Univ. 2003;
Jiatong Univ Beijing 2007;


Selected works

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Journal articles

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  • Roizman, Bernard (1974). "Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins". J. Virol. 114: 8–19. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1975). "Regulation of herpesvirus macromolecular synthesis: Sequential transition of polypeptide synthesis requires functional viral polypeptides". Proc. Nat. Acad. Sci. (USA). 72 (4): 1276–1280. doi:10.1073/pnas.72.4.1276. PMC 432515. PMID 165503. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1980). "Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions". Cell. 22 (1 Pt 1): 243–255. doi:10.1016/0092-8674(80)90172-5. PMID 6253078. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1981). "Regulation of α genes of herpes simplex virus: expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters". Cell. 24 (2): 555–565. doi:10.1016/0092-8674(81)90346-9. PMID 6263501. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1981). "A generalized technique for deletion of specific genes in large genomes: α gene 22 of herpes simplex virus 1 is not essential for growth". Cell. 25 (1): 227–232. doi:10.1016/0092-8674(81)90247-6. PMID 6268303. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1985). ". Herpes simplex virus mutant deleted in the α22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice". J. Virol. 55 (2): 338–346. doi:10.1128/jvi.55.2.338-346.1985. PMC 254938. PMID 2991560. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1985). "Genetic engineering of novel genomes of large DNA viruses". Science. 229 (4719): 1208–1218. doi:10.1126/science.2994215. PMID 2994215. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1987). "The herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture". J. Virol. 61: 896–901. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1992). "The UL13 gene of herpes simplex virus 1 encodes the functions for posttranslational processing associated with phosphorylation of the regulatory protein α22". Proc. Nat. Acad. Sci. (USA). 89: 310–314. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1993). "Repression of the herpes simplex virus 1 α4 gene by its gene product occurs within the context of the viral genome and is associated with all three identified cognate sites". Proc. Nat. Acad. Sci. (USA). 90: 286–290. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1998). "Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins". Gene Ther. 5 (1): 121–130. doi:10.1038/sj.gt.3300550. PMID 9536273. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (1999). "Functional anatomy of the herpes simplex virus 1 overlapping genes encoding infected cell-protein 22 and US1.5 protein". J. Virol. 73 (5): 4305–4315. doi:10.1128/JVI.73.5.4305-4315.1999. PMC 104212. PMID 10196329. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (2007). "Mapping of key functions of the herpes simplex virus 1 US3 protein kinase: the US3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides". J. Virol. 81 (4): 1980–1998. doi:10.1128/JVI.02265-06. PMC 1797600. PMID 17151133. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  • Roizman, Bernard (2008). "Proteolytic cleavage of VP1-2 is required for the release of herpes simplex virus 1 DNA into the nucleus". J. Virol. 82: 2211–2219. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)

Notes

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