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irving Myron Klotz
Born(1916-01-22)January 22, 1916
DiedApril 27, 2005(2005-04-27) (aged 89)
NationalityAmerican
Alma materUniversity of Chicago
Known forLigand-receptor interactions
Scientific career
FieldsBiophysical Chemistry
InstitutionsNational Academy of Sciences
Northwestern University
Doctoral advisorT. F. Young

Irving M. Klotz (January 22, 1916 – April 27, 2005) was an American chemist. He was noted particularly for his work on proteins, using concepts drawn from physical chemistry to understand their interactions with other molecules.[1]

Early life and education

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Klotz studied Chemistry at the University of Chicago, obtaining a S.B. in 1937 and a Ph.D. in 1940.

Career

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In late 1940, Klotz became a research associate at Northwestern University, where he would spend the rest of his career. Unlike a typical postdoctoral appointment, he worked on secret wartime research projects selected by the National Defense Research Committee and taught two classes.[2][1] He continued various NDRC projects involving gasses, filters, and the use of spectrophotometric methods for the rest of the war, including after his 1942 appointment as an instructor.

Original, now in its seventh edition.[3]

Klotz engaged in skeptical inquiry.[4]

Honors and awards

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Klotz was the recipient of the 1949 American Chemical Society Eli Lilly Award in Biological Chemistry, He was elected a fellow of the American Academy of Arts and Sciences in 1968, a member of the National Academy of Sciences in 1970, and a fellow of the Royal Society of Medicine in 1971.

Personal life

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In 1947, he married Themis Askounis Klotz, with whom he had a son, Edward, and a daughter, Audie. In 1966, he married Mary Sue Hanlon Klotz, later a professor of Biochemistry and Molecular Genetics at the University of Illinois at Chicago, with whom he had a son, David.[1]

Selected bibliography

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  • Klotz, Irving M. (1997). Ligand-Receptor Energetics: A Guide for the Perplexed. New York: Wiley.
  • Klotz, Irving M. (1986). Diamond Dealers and Feather Merchants: Tales from the Sciences. Boston: Birkhäuser.
  • Klotz, Irving M. (1950). Chemical Thermodynamics: Basic Theory and Methods. New York: Prentice Hall.

References

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  1. ^ a b c Schachman, Howard (2011). "Biographical Memoir: Irving Myron Klotz (1916 - 2005)" (PDF). nasonline.org. Retrieved 19 January 2019.
  2. ^ Klotz, Irving M. (2004). "Ligand-Receptor Complexes: Origin and Development of the Concept". Journal of Biological Chemistry. 279 (1): 1–12. doi:10.1074/jbc.X300006200. PMID 14604979.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  3. ^ Klotz, Irving M.; Rosenberg, Robert M. (2008). Chemical Thermodynamics: Basic Theory and Methods (7th ed.). New York: Wiley. ISBN 978-0-471-78015-1.
  4. ^ Klotz, I. M. (1988). "The chemical death of Lot's wife: discussion paper". Journal of the Royal Society of Medicine. 81 (7): 397–398. ISSN 0141-0768. PMC 1291670. PMID 3045312.{{cite journal}}: CS1 maint: PMC format (link)
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