User:Jlp21k/Acetyltransferase/Bibliography

You will be compiling your bibliography and creating an outline of the changes you will make in this sandbox.

Bibliography

As you gather the sources for your Wikipedia contribution, think about the following:

Is the source from a reliable publication?
- Reliable publications include established newspapers, academic journals and books, textbooks, and other published sources with reputations for accuracy and fact-checking.
- Unreliable sources include blog posts and other self-published works, press releases, and social media posts.
Is the source verifiable?
- In order for a source to be considered verifiable, other editors should be able to consult the source.
Is the source independent of the subject?
- Is the source connected in any way to the subject? This is especially important when writing biographies or about organizations.
- For example, if you were writing a biography, sources like the person's webpage or personal blog would not be considered independent.
Is the source primary or secondary?
- Primary sources include first-hand accounts, autobiographies, and other original content.
- Wikipedia allows limited use of primary sources, but typically only for straightforward, descriptive statements of facts, and only if they are published and verifiable without requiring specialized knowledge.
- Secondary sources should be the main basis for a biography on Wikipedia.
If you're working on a topic related to medicine or psychology, ensure that your sources follow these special guidelines.
If you're creating a new article, consider the following:
- Ensure that your topic meets Wikipedia's notability guidelines.
- In order for a topic to meet the notability requirement, you must be able to identify 2-3 sources that are reliable, verifiable, and independent of the subject you're writing about.
- Finding sufficient sources to establish notability can be especially hard when writing about people or organizations.
- Sources that are not independent of the subject might be useful additions, but don't count towards the notability requirement.
- Wikipedia has developed special guidelines for writing about living persons. Please follow these carefully.
- Wikipedia has a series of guidelines for writing about different categories of people, such as academics and artists. If you're trying to create a new entry about a living person, please look at these carefully.

If you're not sure whether a source is reliable, ask a librarian! If you have questions about Wikipedia's sourcing rules, you can use the Get Help button below to contact your Wikipedia Expert.

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Bibliography

Examples:

Luke, Learie. 2007. Identity and secession in the Caribbean: Tobago versus Trinidad, 1889–1980 Kingston, Jamaica: University of the West Indies Press.
- This is a book published by a university press, so it should be a reliable source. It also covers the topic in some depth, so it's helpful in establishing notability.
Galeano, Gloria; Bernal, Rodrigo (2013-11-08). "Sabinaria , a new genus of palms (Cryosophileae, Coryphoideae, Arecaceae) from the Colombia-Panama border". Phytotaxa.
- This is a peer-reviewed scientific journal, so it should be a reliable source. It covers the topic in some depth, so it's helpful in establishing notability.
Baker, William J.; Dransfield, John (2016). "Beyond Genera Palmarum: progress and prospects in palm systematics". Botanical Journal of the Linnean Society.
- This is a peer-reviewed scientific journal, so it should be a reliable source for a specific fact. Since it only dedicates a few sentences to the topic, it can't be used to establish notability.

References

1. Marmorstein R, Zhou MM. Writers and readers of histone acetylation: structure, mechanism, and inhibition. Cold Spring Harb Perspect Biol. 2014 Jul 1;6(7):a018762. doi: 10.1101/cshperspect.a018762. PMID: 24984779; PMCID: PMC4067988.

2. Verreault, A., Kaufman, P. D., Kobayashi, R., & Stillman, B. (1998). Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase. Current biology : CB, 8(2), 96–108. https://doi.org/10.1016/s0960-9822(98)70040-5

3. Kim, A. R., Rylett, R. J., & Shilton, B. H. (2006). Substrate binding and catalytic mechanism of human choline acetyltransferase. Biochemistry, 45(49), 14621–14631. https://doi.org/10.1021/bi061536l

4. Strauss, W. L., Kemper, R. R., Jayakar, P., Kong, C. F., Hersh, L. B., Hilt, D. C., & Rabin, M. (1991). Human choline acetyltransferase gene maps to region 10q11-q22.2 by in situ hybridization. Genomics, 9(2), 396–398. https://doi.org/10.1016/0888-7543(91)90273-h

5. Coon, S. L., Mazuruk, K., Bernard, M., Roseboom, P. H., Klein, D. C., & Rodriguez, I. R. (1996). The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression. Genomics, 34(1), 76–84. https://doi.org/10.1006/geno.1996.0243

6. Arnesen, T., Van Damme, P., Polevoda, B., Helsens, K., Evjenth, R., Colaert, N., Varhaug, J. E., Vandekerckhove, J., Lillehaug, J. R., Sherman, F., & Gevaert, K. (2009). Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proceedings of the National Academy of Sciences of the United States of America, 106(20), 8157–8162. https://doi.org/10.1073/pnas.0901931106

7. Van Damme, P., Lasa, M., Polevoda, B., Gazquez, C., Elosegui-Artola, A., Kim, D. S., De Juan-Pardo, E., Demeyer, K., Hole, K., Larrea, E., Timmerman, E., Prieto, J., Arnesen, T., Sherman, F., Gevaert, K., & Aldabe, R. (2012). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. Proceedings of the National Academy of Sciences of the United States of America, 109(31), 12449–12454. https://doi.org/10.1073/pnas.1210303109

8. Hong, H., Cai, Y., Zhang, S., Ding, H., Wang, H., & Han, A. (2017). Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB. Structure (London, England : 1993), 25(4), 641–649.e3. https://doi.org/10.1016/j.str.2017.03.003

**These are the references for the table**

**Below are references for potential text to be added**

Christensen, D. G., Xie, X., Basisty, N., Byrnes, J., McSweeney, S., Schilling, B., & Wolfe, A. J. (2019). Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions. Frontiers in microbiology, 10, 1604. https://doi.org/10.3389/fmicb.2019.01604

Outline of proposed changes

Acetyltransferase	Substrate	Gene (Human)	Chromosome Location (Human)	Gene Group	Abbreviation
Histone Acetyltransferase	Lysine residues on histones¹	HAT1²	2q31.1²	Lysine acetyltransferases²	HAT
Choline Acetyltransferase	Choline³	CHAT⁴	10q11.23⁴	NA	ChAT³
Serotonin N-Acetyltransferase	Serotonin	AANAT⁵	17q25.1⁵	GCN5 Related N-Acetyltransferases⁵	AANAT⁵
NatA Acetyltransferase	N-terminus of various proteins as they emerge from the ribosome	NAA15⁶	4q31.1⁶	Armadillo like helical domain containing N-alpha-acetyltransferase subunits⁶	NatA⁶
NatB Acetyltransferase	Peptides starting with Met-Asp/Glu/Asn/Gln⁸	NAA25⁷	12q24.13⁷	N-alpha-acetyltransferase subunits MicroRNA protein coding host genes⁷	NatB⁷

After the opening sentences, perhaps add sentence discussing the relevance of acetylation, and how it can impact the chemical properties of the substrate (like below, for example).

Acetylation serves as a modification that can profoundly transform the functionality of a protein by modifying various properties like hydrophobicity, solubility, and surface attributes. These alterations have the potential to influence the protein's conformation and its interactions with substrates, cofactors, and other macromolecules.

Now that you have compiled a bibliography, it's time to plan out how you'll improve your assigned article.

In this section, write up a concise outline of how the sources you've identified will add relevant information to your chosen article. Be sure to discuss what content gap your additions tackle and how these additions will improve the article's quality.

Consider other changes you'll make to the article, including possible deletions of irrelevant, outdated, or incorrect information, restructuring of the article to improve its readability or any other change you plan on making. This is your chance to really think about how your proposed additions will improve your chosen article and to vet your sources even further.

Note: This is not a draft. This is an outline/plan where you can think about how the sources you've identified will fill in a content gap.

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