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User:Daviddecraene

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Who am I?

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Ph. D. Biomedical Sciences.
Owner of Ontology Online
Creator of jOWL - semantic javascript library.

Expertise in the following fields:

Currently employed by Language and Computing.

Publications

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Biomedical sciences

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Decraene D. et al
JID 125(5): 1026-31. 2005.
A low UVB dose, with the potential to trigger a protective p53-dependent gene program, increases the resilience of keratinocytes against future UVB insults.

Decraene D. et al
JID 123(1): 207-12. 2004.
AKT status controls susceptibility of malignant keratinocytes to the early-activated and UVB-induced apoptotic pathway.

Decraene D. et al
JID 122(2): 484-91. 2004.
A synthetic superoxide dismutase/catalase mimetic (EUK-134) inhibits membrane-damage-induced activation of mitogen-activated protein kinase pathways and reduces p53 accumulation in ultraviolet B-exposed primary human keratinocytes.

Decraene D.et al
JBC 277(36): 32587-95. 2002.
Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes.

Decraene D. et al
J Photochom & Photobiol. 63(1-3):78-83. 2001.
Acute response of human skin to solar radiation: regulation and function of the p53 protein.

Claerhout S., Decraene D.et al
JID, advance online publication. august 2006.
AKT Delays the Early-Activated Apoptotic Pathway in UVB-Irradiated Keratinocytes Via BAD Translocation.


PH.D. Dissertation:
The UVB-response in human skin and its modulation by the proto-oncogenic AKT signaling pathway.

Ontology

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The Methodology behind the Military Health System Conceptual Framework and Core Ontology.
Mariana Casella dos Santos, Christoffel Dhaen, David Decraene, Maria van Gurp, Tom Deray.

CliniComp Terminology Mapping: Methodology
David Decraene, Karen Doyle, Dave Hellman & Mariana Casella dos santos.