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This is a list of natural product-based drugs. This list includes natural products that are used directly as drugs, semisynthetic natural product drugs, as well as fully synthetic drugs that are inspired by natural products.[1][2]
Year of introduction | Generic name (trade name) | Lead compound | Classification | Therapeutic indication |
---|---|---|---|---|
1998 | orlistat (Xenical) | lipstatin | semi-synthetic NP | antiobesity |
Amrubicin | Example | Example | Example | |
Amrubicin | Example | Example | Example | |
Anidulafungin | Example | Example | Example | |
Apomorphine | Example | Example | Example | |
Artemotil | Example | Example | Example | |
Aztreonam | Example | Example | Example | |
Biapenem | Example | Example | Example | |
Bivalirudin | Example | Example | Example | |
Bleomycin | Example | Example | Example | |
Capsaicin | Example | Example | Example | |
Caspofungin | Example | Example | Example | |
Cefditoren | Example | Example | Example | |
Cocaine | Example | Example | Example | |
Codinaeopsin | Example | Example | Example | |
Colchicine | Example | Example | Example | |
Daptomycin | Example | Example | Example | |
Dimethyltryptamine | Example | Example | Example | |
Doripenem | Example | Example | Example | |
Dronabinol | Example | Example | Example | |
Ergotamine | Example | Example | Example | |
Ertapenem | Example | Example | Example | |
Everolimus | Example | Example | Example | |
Exenatide | Example | Example | Example | |
Fumagillin | Example | Example | Example | |
Galantamine | Example | Example | Example | |
Ixabepilone | Example | Example | Example | |
Lisdexamfetamine | Example | Example | Example | |
Mescaline | Example | Example | Example | |
Micafungin | Example | Example | Example | |
Miglustat | Example | Example | Example | |
Morphine | Example | Example | Example | |
Mycophenolate | Example | Example | Example | |
Nitisinone | Example | Example | Example | |
Paclitaxel | Example | Example | Example | |
Phenethylamine | Example | Example | Example | |
Pimecrolimus | Example | Example | Example | |
Retapamulin | Example | Example | Example | |
Romidepsin | Example | Example | Example | |
Rosuvastatin | Example | Example | Example | |
Spiruchostatins | Example | Example | Example | |
Telavancin | Example | Example | Example | |
Telithromycin | Example | Example | Example | |
Temsirolimus | Example | Example | Example | |
Tigecycline | Example | Example | Example | |
Tiotropium | Example | Example | Example | |
Trabectedin | Example | Example | Example | |
Ziconotide | Example | Example | Example | |
Zotarolimus | Example | Example | Example |
A number of drugs have been derived from biological sources in nature, these include:[3]
References
[edit]- ^ Butler MS (2008). "Natural products to drugs: natural product-derived compounds in clinical trials". Nat Prod Rep. 25 (3): 475–516. doi:10.1039/b514294f. PMID 18497896.
- ^ Newman DJ, Cragg GM (2012). "Natural products as sources of new drugs over the 30 years from 1981 to 2010". J. Nat. Prod. 75 (3): 311–35. doi:10.1021/np200906s. PMC 3721181. PMID 22316239.
- ^ Cite error: The named reference
CRC Press
was invoked but never defined (see the help page).