User:Bella2021gg/Human germline engineering
Ideas for Human Germline Engineering
remove subjective terms: sparked, much, significant
- This article is lengthy already, however I believe it could use more sources that are within the past 3 years, including some sources I used for my Project 2 that I got off of Web of Science.
- More information on germline editing of other animals other than humans can be used to compare to possible effects of human germline editing.
- I think the article should have a section on global policy, as the limited global policy is mixed into a "current state of research" heading. Many countries have outlawed the practice and therefor stunted research, and the specifics could be beneficial. Other countries have not explicitly outlawed the practice, leading to gray areas where experimentation could possibly be conducted.
- There are no images, which could be a good addition, especially for showing global policy or how CRISPR can be used to edit human germline cells.
- The writing is fairly easy to follow and seems like it has adequate understandability, so I will reflect that in my writing.
- current sources of policy are from 2014-2016, use
Marchant, G. E. (2021). Global Governance of Human Genome Editing: What Are the Rules? Annual Review of Genomics and Human Genetics, Vol 22, 2021. A. Chakravarti and E. D. Green. 22: 385-405.
- paragraph on designer babies can be added that non-therapeutic changes are a gray area and not defined, use
(1) Greene, M. and Z. Master (2018). "Ethical Issues of Using CRISPR Technologies for Research on Military Enhancement." Journal of Bioethical Inquiry 15(3): 327-335.
- include precautionary principle in ethics debate seciton, use
Greene, M., & Master, Z. (2018). Ethical Issues of Using CRISPR Technologies for Research on Military Enhancement. Journal of Bioethical Inquiry, 15(3), 327-335. doi:10.1007/s11673-018- 9865-6
- add section on non-human CRISPR germline editing that may show how it will work on humans, use
Li, R. Q., et al. (2020). "Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs." Transgenic Research 29(1): 149-163.
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