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User:Bamba1999/Management of HIV/AIDS

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Research

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Patients Cured of HIV

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Alternative approaches aiming to mimic one’s biological immunity to HIV through the absence or mutation of the CCR5 gene is being conducted in current research efforts. The efforts of which are done through the introduction of induced pluripotent stem cells that have been CCR5 disrupted through the CRISPR/Cas9 gene editing system.

References

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  Charpentier, Emmanuelle. “CRISPR‐Cas9: How Research on a Bacterial RNA‐guided Mechanism Opened New Perspectives in Biotechnology and Biomedicine.” EMBO molecular medicine 7.4 (2015): 363–365. Web.

  Kang, HyunJun et al. “CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-Tropic HIV-1 Virus.” Molecular therapy. Nucleic acids 4.C (2015): e268–e268. Web.