User:167B/Lipopeptide
Many bacteria produced these molecules as a part of their metabolism, especially those of the genus Bacillus, Pseudomonas and Streptomyces. Certain lipopeptides are used as antibiotics. (this is taken from the real wikipedia page, so I know what to write next)
this is what i am planning to add on: first explaining a bit how lipopeptides function as antibiotic
Due to the structural and molecular properties such as the fatty acid chain, it poses the effect of weakening the cell function or destroying the cell.[1][2]
second: explaining how the length of carbons plays a role
Therefore, an increase in the alkyl chain can make lipopeptides soluble in water.[1]As well, it opens the cell membrane of the bacteria, so antimicrobial activity can take place.[3]
*for the last sentence I am reusing the same resources from author Czechowicz,
sources
Czechowicz, Paulina and Nowicka, Joanna. "ANTIMICROBIAL ACTIVITY OF LIPOPEPTIDES" Advancements of Microbiology, vol.57, no.3, 2018, pp.213-227. https://doi.org/10.21307/PM-2018.57.3.213
- This is a scholar journal published by Sciendo, it does have very detailed information about the topic.
Raaijmakers, Jos M et al. “Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics.” FEMS microbiology reviews vol. 34,6 (2010): 1037-62. doi:10.1111/j.1574-6976.2010.00221.x
- This is a peer reviewed journal on PubMed, which is a realible source
Nasompag, Sawinee, et al. “Effect of Acyl Chain Length on Therapeutic Activity and Mode of Action of the CX-KYR-NH2 Antimicrobial Lipopeptide.” Biochimica et Biophysica Acta. Biomembranes, vol. 1848, no. 10, 2015, pp. 2351–64, https://doi.org/10.1016/j.bbamem.2015.07.004.
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[edit]Article body
[edit]References
[edit]- ^ a b Czechowicz, Paulina; Nowicka, Joanna (2018-01-01). "ANTIMICROBIAL ACTIVITY OF LIPOPEPTIDES". Postępy Mikrobiologii - Advancements of Microbiology. 57 (3): 213–227. doi:10.21307/PM-2018.57.3.213. ISSN 2545-3149.
- ^ Raaijmakers, Jos M.; De Bruijn, Irene; Nybroe, Ole; Ongena, Marc (2010-11). "Natural functions of lipopeptides from Bacillus and Pseudomonas : more than surfactants and antibiotics". FEMS Microbiology Reviews. 34 (6): 1037–1062. doi:10.1111/j.1574-6976.2010.00221.x. ISSN 1574-6976.
{{cite journal}}: Check date values in:|date=(help) - ^ Nasompag, Sawinee; Dechsiri, Punpimon; Hongsing, Nuttaya; Phonimdaeng, Prasart; Daduang, Sakda; Klaynongsruang, Sompong; Camesano, Terri A.; Patramanon, Rina (2015-10). "Effect of acyl chain length on therapeutic activity and mode of action of the CX-KYR-NH2 antimicrobial lipopeptide". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848 (10): 2351–2364. doi:10.1016/j.bbamem.2015.07.004.
{{cite journal}}: Check date values in:|date=(help)