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Trimethoprim/sulfadoxine

From Wikipedia, the free encyclopedia
Trimethoprim/sulfadoxine
Combination of
TrimethoprimDihydrofolate reductase inhibitor
SulfadoxineSulfonamide antibiotic
Clinical data
Trade namesTrimidox
Identifiers
CAS Number

Trimethoprim/sulfadoxine, sold under the brand name Trimidox, is an antibacterial agent that is used in cattle and swine to prevent and treat infections by both gram-negative and gram-positive bacteria.[1]

Veterinary uses

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Trimethoprim/sulfadoxine is used in the treatment of swine and cattle, including dairy cattle, beef cattle and veal.

In cattle, it is used to treat:

In swine, it is used to treat:

Contraindications

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Trimethoprim/sulfadoxine is contraindicated in cattle or swine that show marked liver parenchymal damage or blood dyscrasias, or those with a history of sulfonamide sensitivity.[1]

Milk from an animal treated with trimethoprim/sulfadoxine must not be consumed for at least 96 hours following the most recent treatment; treated animals must not be slaughtered for use in food for at least ten days after the last treatment.[1]

References

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  1. ^ a b c d e f g h i "Trimidox". Vetoquinol Canada Inc. Retrieved 11 November 2011.