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TraJ 5' UTR

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traJ 5' UTR
Identifiers
SymboltraJ_5
RfamRF00243
Other data
RNA typeCis-reg
Domain(s)Bacteria
SOSO:0000204
PDB structuresPDBe

The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.

In conjugating bacteria the FinOP system regulates the transfer of F-like plasmids. The FinP gene encodes an antisense RNA product that is complementary to part of the 5' UTR of the traJ mRNA.[1] The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.

References

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  1. ^ Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J. 22 (23): 6346–6355. doi:10.1093/emboj/cdg607. PMC 291848. PMID 14633993.
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