Template:2022 NISA East standings
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Qualification |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Chattanooga FC | 16 | 9 | 4 | 3 | 30 | 12 | +18 | 31 | Qualification for the semi-finals |
| 2 | Michigan Stars FC | 15 | 6 | 6 | 3 | 18 | 9 | +9 | 24 | Qualification for the play-offs |
| 3 | Maryland Bobcats FC | 15 | 6 | 3 | 6 | 24 | 19 | +5 | 21 | |
| 4 | Syracuse Pulse | 16 | 5 | 2 | 9 | 18 | 23 | −5 | 17 | |
| 5 | Flower City Union | 19 | 2 | 2 | 15 | 10 | 50 | −40 | 8 |
Updated to match(es) played on August 20, 2022. Source: nisasoccer.com
Rules for classification: 1) points; 2) goal differential; 3) goals scored; 4) head-to-head
Rules for classification: 1) points; 2) goal differential; 3) goals scored; 4) head-to-head