Template:1943 American League standings
| Team | W | L | Pct. | GB | Home | Road |
|---|---|---|---|---|---|---|
| New York Yankees | 98 | 56 | .636 | — | 54–23 | 44–33 |
| Washington Senators | 84 | 69 | .549 | 13½ | 44–32 | 40–37 |
| Cleveland Indians | 82 | 71 | .536 | 15½ | 44–33 | 38–38 |
| Chicago White Sox | 82 | 72 | .532 | 16 | 40–36 | 42–36 |
| Detroit Tigers | 78 | 76 | .506 | 20 | 45–32 | 33–44 |
| St. Louis Browns | 72 | 80 | .474 | 25 | 44–33 | 28–47 |
| Boston Red Sox | 68 | 84 | .447 | 29 | 39–36 | 29–48 |
| Philadelphia Athletics | 49 | 105 | .318 | 49 | 27–51 | 22–54 |