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Tektin-1

From Wikipedia, the free encyclopedia
TEKT1
Identifiers
AliasesTEKT1, tektin 1
External IDsOMIM: 609002; MGI: 1333819; HomoloGene: 7973; GeneCards: TEKT1; OMA:TEKT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_053285

NM_001282006
NM_001282007
NM_011569

RefSeq (protein)

NP_444515

NP_001268935
NP_001268936
NP_035699

Location (UCSC)Chr 17: 6.79 – 6.83 MbChr 11: 72.24 – 72.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tektin-1 is a protein that in humans is encoded by the TEKT1 gene.[5][6]

Function

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This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167858Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020799Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: tektin 1".
  6. ^ Xu M, Zhou Z, Cheng C, Zhao W, Tang R, Huang Y, Wang W, Xu J, Zeng L, Xie Y, Mao Y (December 2001). "Cloning and characterization of a novel human TEKTIN1 gene". Int. J. Biochem. Cell Biol. 33 (12): 1172–82. doi:10.1016/S1357-2725(01)00089-9. PMID 11606253.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.