Talk:Voltage-gated potassium channel

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The mechanism of K+ channel inactivation

For what I know, the tethered ball model is a Na+ only thing, as the current citation suggests. (One of them points to an article about Na+ channel.) Can someone kindly provide a source in which such analogy is used for K+ channel?

And, nevertheless, the ball-blocking-hole picture is an analogy at best. 冷雾 (talk) 04:06, 29 July 2013 (UTC)[reply]

No, the N-inactivation gate is also found in many potassium channels as documented by reference 10 (PMID 8133246). Boghog (talk) 07:12, 29 July 2013 (UTC)[reply]

PMID 11390785 is a better citation that documents the ball and chain model of potassium channel inactivation. I have added this citation to the article. Boghog (talk) 23:14, 29 July 2013 (UTC)[reply]

What's the trigger voltage?

I've seen a youtube that said that the v-gated K channel triggers at +30 mV, but have not been able to find anything else that says that, so maybe this would be a good place to have that information, if available? UnderEducatedGeezer (talk) 00:12, 5 November 2017 (UTC)[reply]

I agree with you that it would be a good idea to cover that at this page. This is specifically about the threshold potential for the K channels. It's significantly and importantly different for the "delayed rectifiers" and "A channels" that are listed on this page. Here is a good source for both (along with a "fast" current that we can probably leave out as having low due weight): [1]. It puts the threshold for A channels at about –45 mV and for delayed rectifiers at about –25 mV. (I think what you saw on YouTube was probably looking high because of the delayed time course.) Another source puts the number for A channels at about –60 mV: [2]. --Tryptofish (talk) 16:42, 5 November 2017 (UTC)[reply]