Talk:Viral vector vaccine

Did you know nomination

The following is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.

The result was: promoted by Vaticidalprophet (talk) 10:32, 20 April 2021 (UTC)

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• ... that viral vector vaccines currently in use include four COVID-19 vaccines and two Ebola vaccines?

• Reviewed: Smell training

Created by John P. Sadowski (NIOSH) (talk). Self-nominated at 01:17, 10 April 2021 (UTC).

• New enough and long enough. QPQ present. Hook fact checks out to the multicited list of COVID vaccines and the two Ebola vaccines mentioned in the History section. No other textual issues. Good to go and will certainly be a much consulted page in the year to come. Sammi Brie (she/her • t • c) 22:34, 14 April 2021 (UTC)

"incapable of replication"

The article states: "most viral vectors are designed to be incapable of replication because the necessary genes are removed". Perhaps the article should mention that such viruses can still replicate (be grown) in complementing cell lines that express the missing viral gene product(s). Without that information, some readers may think the description is inaccurate or misleading (how can you produce large quantities if they can't replicate?), and assume that the genes are removed only after growing the viruses in culture (similar to how inactivated vaccines are produced). Prevalence 23:54, 1 May 2021 (UTC)

Genetically modified vaccine

So the page Genetically modified vaccine, might it be fit for merger, inclusion (inline wikification) or an more encompassing redirect, or is it sufficiently differing in scope (the specific ref. given seems to be a specific kind of the page name, which may require retitling) Nagelfar (talk) 19:02, 24 August 2021 (UTC)

Vector-vaccines since 2003

In Germany a viral vector vaccine against Equine influenza is available since 2003 https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0029-1237609 I think the use of viral vectors in veterinary medicine should be part of the history section. --Manorainjan 09:18, 27 December 2021 (UTC)

Wikipedia Editing Course:Recent developments in Biotechnology

HI,I'm an MS student of the Department of Molecular Biology at Uskudar University.This article is a Wikipedia editing project assigned as a part of the postgraduate coursework on " Recent Developments in Biotechnology MLC501". Student editor@Chinemerem M Nnadi (talk) 22:16, 8 December 2022 (UTC).https://outreachdashboard.wmflabs.org/courses/Uskudar_University,_Istanbul,_Turkiye/MLC501_Recent_Developments_in_Biotechnology_2022-2023_Fall_(2022-2023)/home -- Template:Unsigned -->— Preceding unsigned comment added by Chinemerem M Nnadi (talk • contribs) 10:14, 11 December 2022 (UTC)

Disadvantage of Adenovirus vectors

the article states"A disadvantage is that many people have pre-existing immunity to adenoviruses due to previous exposure". I think more explanation and discussion should be added because studies on overcoming pre‐existing immunity and boosting vaccine‐induced antigen‐specific immunogenicity are still ongoing".

Chinemerem M Nnadi (talk) 18:08, 13 December 2022 (UTC)

Route of administration

The introduction of alternate routes for immunization of viral vector vaccines can induce mucosal immunology at site of administration thereby limiting respiratory or gastrointestinal infections.This include intranasal,aerosol,intradermal and oral routes of vaccination.Studies are being made on how these diverse routes can be used to overcome the neutralising anyibodies limitations of these vaccines.i think its worth discussing. Chinemerem M Nnadi (talk) 22:01, 26 December 2022 (UTC)

"others"

the article stated adenovirus vector and "others"

Although Adenovirus vectors are most commonly used,there are other viral vectors that needs to be introduced like Poxviruses, Rhabdoviruses, Paramixoviruses, Arenaviruses and Herpesviruses.What do you think? Chinemerem M Nnadi (talk) 22:22, 26 December 2022 (UTC)

Copy Edit Tag

Hi @RealPharmer3. I hope you're doing well! I'm reaching out for help in addressing the copy edit tag on this article. I took a shot at copy editing already, but am not too familiar with the technical information. I see you've recently made contributions to this article, and it seems you're comfortable (or at least more comfortable than myself) with the information. Would you mind taking a look at the article and looking for potential copy edits, if any at all? I'd like to have someone who has a better understanding of the content take a look before removing the tag. Thanks for your time! Jadedhippo (talk) 02:48, 1 March 2023 (UTC)

Hi @Jadedhippo Yes, of course! Thanks for reaching out. I'll take a look at the article and let you know. RealPharmer3 (talk) 05:06, 1 March 2023 (UTC)

Hi @Jadedhippo Thank you for doing some cleaning on this. I just went through the article and it looks like it's in a good place now. RealPharmer3 (talk) 16:52, 1 March 2023 (UTC)

Thanks for taking the time to help out, @RealPharmer3! I'll go ahead and remove the tag. Jadedhippo (talk) 01:35, 2 March 2023 (UTC)