Talk:Tofisopam
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levotofisopam
[edit]The other optical isomer unexpectedly lowered serum urate, which led to clinical trials for gout. --Nbauman (talk) 20:39, 15 December 2012 (UTC)
Analogues
[edit]US Patent 5288863 gives a large series of homologues. It seems that the molecule is optimized apart from substitution of the benzene ring and that an EWG at the 2 position gives the strongest analogues (x3.77 stronger than tofisopam). The chemistry appears to use lithium perchlorate etherate for ring-expansion (O swapped for hydrazine). Friskly perchlorates are NOT something to be taken lightly. — Preceding unsigned comment added by Dvwynn (talk • contribs) 13:41, 26 October 2014 (UTC)
External links modified
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