Talk:Tametraline

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Tametraline.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

this was horribly edited (with some opinion lumped in) and needs a fix

Stereochemistry

Calling Zoloft^® "3,4-dichloro tametraline" is weasel language on 2 counts.

Firstly, it overlooks the fact that sertraline is the SS isomer, whereas tametraline would have been marketed as the 1R/4S salt.

Secondly, Zoloft is a brand name that is specifically referring to the sertraline.HCl marketed by Pfizer and not just sertraline. —Preceding unsigned comment added by Nuklear (talk • contribs) 09:46, 9 August 2009

This talk page comment moved from the article Astronaut (talk) 12:45, 9 August 2009 (UTC)[reply]

A couple of points: Adding ".HCl" after sertraline is confusing (I thought you had forgotten the space at the end of the sentence and randomly added HCl for some reason) - would "-hydrochloride" be a better wording? And what do "SS isomer" and "1R/4S salt" mean? - I think the relationship between tametraline and sertraline is better expressed in this article with "3,4-dichloro ...". Readers can click on the sertraline link if they wish to learn more about that compound and its use in Zoloft.

As for Zoloft itself, the article linked to is the generic compound sertraline. Its use in Zoloft is almost coincidental. As a general rule you should not give undue weight to a commercial product, eg. compare the article on the generic painkiller Ibuprofen to the articles on the commercial products Advil and Nurofen. Also note that on Wikipedia we generally avoid ®, ©, ™ and other markings that express "ownership" of a word or phrase. Astronaut (talk) 13:13, 9 August 2009 (UTC)[reply]