Talk:SUMO protein

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Low-importance).

Untitled

Please, give the phonetic transcription of the word "Sumoylation". 93.81.94.22 (talk) 20:02, 10 June 2009 (UTC) AnOther Observer[reply]

deleted sentence fragments

I deleted the following from the SUMO attachment section. It should be converted to full sentences with citations if it is relevant and correct.

balance SUMO equilibrium is important for the cell. Reduced or enhanced SUMOlyation will lead to onsets of cancers, for example, prostat cancer lead to eleveated expression of SENP1 or SENP3, breast cancer increased modification of SUMO targets via, (I)induction of Ubc9 E2 ligase (II)PIAS3 E3 ligase (III)cocurrent decrease in SENP6

Biolprof (talk) 17:40, 17 August 2012 (UTC)[reply]

SUMO protease activity is not ATP-dependent. E.g. the E1 activity is, I guess that was confused. I removed the wrong parts and leave it to the author to rephrase the sentence with regards to the ATP-dependence of other processes relevant here.

--Felix Tritschler (talk) 15:49, 19 October 2012 (UTC)[reply]

Role in Regenerative Medicine

SUMOylation is an important component in many biological processes, and it has applications in developmental biology as well as regenerative medicine which I would like to personally explore in order to at least briefly mention and share new information here:

Neural stem cells
Stem cell maintenance
Skeletal development
Embryonic stem cells
DNA methylation
Cardiology

What this topic page represents is a key fundamental process in biology which may aid researchers in making patients' lives better. I will do my best to make it approachable, and I will at least attempt to improve the organization of this page in the process.

To quote a publication, "More than 53 000 unique SUMOylation sites have been identified in human proteins."

Source: Andrew Vargas Palacios, Pujan Acharya, Anthony Stephen Peidl, Moriah Rene Beck, Eduardo Blanco, Avdesh Mishra, Tasneem Bawa-Khalfe, Subash Chandra Pakhrin, SumoPred-PLM: human SUMOylation and SUMO2/3 sites Prediction using Pre-trained Protein Language Model, NAR Genomics and Bioinformatics, Volume 6, Issue 1, March 2024, lqae011, https://doi.org/10.1093/nargab/lqae011

Any advice in this regard would be most welcome!

Cheers,

SM Salient.Masonry (talk) 18:04, 1 October 2024 (UTC)[reply]