Talk:Opipramol

Pharmacology Mid‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Chemicals Low‑importance

	This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles
Low	This article has been rated as Low-importance on the project's importance scale.

Medicine Mid‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Opipramol.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Untitled

german chapter of wikipedia already has an entry on this [1] --Lieutenant Colonel Frank Slade 03:38, 10 July 2006 (UTC)[reply]

If I think of the structur and effect of other sigma ligands I would believe that Opipramole isn't a sigma agonist. It is a sigma antagonist!!!

Does anybody know opipramol's affinity for particular receptors (σ1 ,σ2, D2, 5-HT2, H1, H2, mACh) -> Ki=???nM

— Preceding unsigned comment added by 93.181.54.235 (talk) 21:18, 14 January 2012 (UTC)[reply]

Bad English or missing words in two sentences?

Sigma receptors as a set of proteins located in the endoplasmic reticulum, σ1 receptors play key role in potentiating intracellular calcium mobilization thereby acting as sensor or modulator of calcium signalling. Occupancy of σ1 receptors by agonists causes translocation of the receptor from endoplasmic reticulum to peripheral areas (membranes) where the σ1 receptors and neurotransmitter release.

Both sentences seem to lack a word or use the wrong verb form. At least I don't understand them. For example: "where the σ1 receptors and neurotransmitter release." Release what? Or "are released"?

Why isn't it used in the USA?

Is there a specific reason known, why it isn't on the market in the USA?