Talk:Obligate activator

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Inaccurate information

This article is based on low-quality sources (USMLE test study guide) and is inaccurate. The information stated here is not found in any other context other than being quoted from this same source. Essential, or "obligate" activators, are just a form of allosteric activators, which only refers to the mechanism in which they function (making conformational changes in an enzyme to increase its affinity). Here source describing N-acetyl-glutamate (mentioned as an example in the article) as an allosteric activator:

"Physical location of the site for N-acetyl-L-glutamate, the allosteric activator of carbamoyl phosphate synthetase, in the 20-kilodalton COOH-terminal domain."^[1]

Therefore, I am merging this article into Allosteric regulation, correcting the content and sources. Ibenami (talk) 23:44, 16 January 2018 (UTC)[reply]

^ Heibel, Sandra Kirsch; Lopez, Giselle Yvette; Panglao, Maria; Sodha, Sonal; Mariño-Ramírez, Leonardo; Tuchman, Mendel; Caldovic, Ljubica; Cheriyath, Venugopalan (27 February 2012). "Transcriptional Regulation of N-Acetylglutamate Synthase". PLoS ONE. 7 (2): e29527. doi:10.1371/journal.pone.0029527.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[1] Heibel, Sandra Kirsch; Lopez, Giselle Yvette; Panglao, Maria; Sodha, Sonal; Mariño-Ramírez, Leonardo; Tuchman, Mendel; Caldovic, Ljubica; Cheriyath, Venugopalan (27 February 2012). "Transcriptional Regulation of N-Acetylglutamate Synthase". PLoS ONE. 7 (2): e29527. doi:10.1371/journal.pone.0029527.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[1]