Talk:Nucleoside-modified messenger RNA

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A fact from Nucleoside-modified messenger RNA appeared on Wikipedia's Main Page in the Did you know column on 28 December 2020 (check views). The text of the entry was as follows:

Did you know... that modified mRNA (mRNA translation depicted) is a key technology in the Moderna and BioNTech/Pfizer vaccines against COVID-19?

A record of the entry may be seen at Wikipedia:Recent additions/2020/December. The nomination discussion and review may be seen at Template:Did you know nominations/Nucleoside-modified messenger RNA.

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The following Wikipedia contributor has declared a personal or professional connection to the subject of this article. Relevant policies and guidelines may include conflict of interest, autobiography, and neutral point of view.
Their edits to this article were last checked for neutrality on 07-12-2020 by Amkgp.

Gnom (talk · contribs) This user has contributed to the article. This user has declared a connection. (here)

How does mRNA leave our bodies, if ever?

I'm far from an expert on molecular genetics, but I kinda understand the workings of these mRNA messenger molecules. I do also understand how it triggers the cell to make the proteins the mRNA encodes for. But I do not understand how the foreign mRNA is treated after a while. Will it decompose after a few days? Will it remain forever in the cell after it entered, until the cell dies? Will it replace the natural occuring RNA in the cell eventually? Will it be dismantled by the immunesystem after a while? What happens to it, after use? I really want that to be found on this wiki page, as I have had multiple discussions about this type of vaccine already and found myself not able to explain in truth what happens with it after the mRNA is used for its protein encoded purpose. Should I say that these foreign mRNA molecules will remain in the cells or will they leave the system? Grifo (talk) 08:19, 15 June 2021 (UTC)[reply]