Talk:Lymphotoxin

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Hello,

While other pages exist for both lymphotoxin alpha and lymphotoxin beta, on this page I plan to provide a general overview about the lymphotoxin protein, its role as a cytokine in the immune system, and a description of each type. I will also elaborate on lymphotoxin involvement in health issues such as cancer and viral infections, and how the protein can be used for treatment of these conditions and related health issues. Below is a list of sources I will use to support the information added.

• Benedict CA, Ware CF (October 2001). "Virus targeting of the tumor necrosis factor superfamily". Virology. 289 (1): 1–5. doi:10.1006/viro.2001.1109. PMID 11601911.
• Schlüter D, Deckert M (August 2000). "The divergent role of tumor necrosis factor receptors in infectious diseases". Microbes and Infection. 2 (10): 1285–92. doi:10.1016/s1286-4579(00)01282-x. PMID 11008118.
• Zhu M, Fu YX (November 2011). "The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling". Immunological Reviews. 244 (1): 75–84. doi:10.1111/j.1600-065X.2011.01061.x. PMID 22017432.
• Ruddle NH (April 2014). "Lymphotoxin and TNF: how it all began-a tribute to the travelers". Cytokine & Growth Factor Reviews. 25 (2): 83–9. doi:10.1016/j.cytogfr.2014.02.001. PMC 4027955. PMID 24636534.

Please let me know if there are additional articles that would benefit the information on this page or if there are any concerns about the listed sources.

Immcarle115 (talk) 20:22, 2 February 2020 (UTC)

Hi,

For lymphotoxin, I am planning to further elaborate on its role in immune regulation, in the context of cancer and other forms of health related maladies. These are the following sources that I will use in order to provide context to lymphotoxin and its significance in certain diseases.

• Sarhan D, Palma M, Mao Y, Adamson L, Kiessling R, Mellstedt H, et al. (June 2015). "Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β". European Journal of Immunology. 45 (6): 1783–93. doi:10.1002/eji.201444885. PMID 25773885.
• Drutskaya M, Atretkhany KS, Zvartsev R, Kruglov A, Nedospasov S (July 2015). "TNF and Lymphotoxin in immune regulation and cancer". FEBS Journal. 282 (SI): 35.
• Gubernatorova EO, Tumanov AV (November 2016). "Tumor Necrosis Factor and Lymphotoxin in Regulation of Intestinal Inflammation". Biochemistry. Biokhimiia. 81 (11): 1309–1325. doi:10.1134/S0006297916110092. PMID 27914457.
• Ruddle NH (April 2014). "Lymphotoxin and TNF: how it all began-a tribute to the travelers". Cytokine & Growth Factor Reviews. 25 (2): 83–9. doi:10.1016/j.cytogfr.2014.02.001. PMID 24636534.

Please let me know if there are other resources I could utilize or concerns about my current sources. Immcarle35 (talk) 21:54, 2 February 2017 (UTC)

In regards to this project, I will be making edits to Lymphotoxin alpha instead of this page since I believe this page is very vague. I think that this page should instead be linked to either lymphotoxin alpha or beta. Thus, everything that is mentioned on this page should be moved to either lymphotoxin alpha or beta.

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Peer reviewers: Immcarle46.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 09:35, 18 January 2022 (UTC)

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 7 January 2020 and 12 March 2020. Further details are available on the course page. Student editor(s): Immcarle115.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 09:35, 18 January 2022 (UTC)