Talk:Luria–Delbrück experiment

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Genetics task force (assessed as High-importance).
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).

History of Science Mid‑importance

	History of science portal This article is part of the History of Science WikiProject, an attempt to improve and organize the history of science content on Wikipedia. If you would like to participate, you can edit the article attached to this page, or visit the project page, where you can join the project and/or contribute to the discussion. You can also help with the History of Science Collaboration of the Month.History of ScienceWikipedia:WikiProject History of ScienceTemplate:WikiProject History of Sciencehistory of science articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Statistics Low‑importance

	This article is within the scope of WikiProject Statistics, a collaborative effort to improve the coverage of statistics on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.StatisticsWikipedia:WikiProject StatisticsTemplate:WikiProject StatisticsStatistics articles
Low	This article has been rated as Low-importance on the importance scale.

Microbiology High‑importance

	This article is within the scope of WikiProject Microbiology, a collaborative effort to improve the coverage of Microbiology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.MicrobiologyWikipedia:WikiProject MicrobiologyTemplate:WikiProject MicrobiologyMicrobiology articles
High	This article has been rated as High-importance on the project's importance scale.

To do

add a brief description of the attempt to extend and evaluate this finding. Various follow-up studies with other systems are reviewed by Sarkar 1991 (Sarkar S. 1991. Lamarck Contre Darwin, Reduction Versus Statistics: Conceptual Issues in the Controversy Over Directed Mutagenesis in Bacteria. In: Tauber AI, editor. Organism and the Origins of Self. Netherlands: Kluwer Academic Publishers. p. 235-271.) Dabs (talk) 18:01, 14 October 2020 (UTC)[reply]
explain that the experiment only shows that some mutations arise prior to selection, and that this became a point of criticism in the directed mutations controversy. See also Sarkar 1991. More recently CRISPR spacer acquisition has been invoked as an exception to spontaneousness in the Luria-Delbrück sense. Dabs (talk) 18:01, 14 October 2020 (UTC)[reply]

comments

There was some silliness about there not being any evidence yet for adaptive mutagenesis - adding a more recent and review on the matter by Foster. 173.53.60.192 (talk) 22:08, 11 January 2014 (UTC)[reply]

Removed replica plating. This is not described in Luria Delbruck.

JimHu 00:26, 7 October 2006 (UTC)[reply]

I have removed this nonsense about the "sophisticated mathematical" model for the plate counts. I first discovered this kind of verbage in my genetics textbook, and was surprised that the authors seemed to casually dismiss Delbruck's analysis as somehow to complicated or not important enough for students to understand. It is in fact the simplicity of their model and the experiment, I think, that was largely responsible for them earning the Nobel prize. People should take the time to understand it. When I have free day, I will set up an article describing the derivation of the Luria-Delbruck distribution.