Talk:Lefetamine

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Lefetamine.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Legality

Changed the legality to Schedule IV for the US. Not sure about other countries, but it is listed on the DEA's list of scheduled drugs. Also the the un-IUPAC name the DEA uses as a synonym. Revaaron (talk) 17:44, 9 January 2008 (UTC)[reply]

Prototype for modern anorexics

More recently, lefetamine has served as a prototype for some more modern anorexics. A good example of this is 'The synthesis of pyrrole analogues of the analgesic drug lefetamine is reported. These derivatives bear the 1-phenyl-2-(1H-pyrrol-1-yl)ethylamino moiety. Compounds were evaluated for analgesic activities in mice by the hot plate and Randall-Selitto tests. Antiinflammatory activity was tested by the carrageenan-induced rat paw edema method. General neuropsychopharmacological effects were also screened. The most interesting compound, N,N-dimethyl-1-phenyl-2-(1H-pyrrol-1-yl)ethylamine, showed an analgesic effect comparable to that of lefetamine, but devoid of the neurotoxicity of this drug.'*

Synthesis, neuropsychopharmacological effects and analgesic-antiinflammatory activities of pyrrole analogues of lefetamine.

Massa S, Stefancich G, Artico M, Corelli F, Silvestri R, Pantaleoni GC, Fanini D, Palumbo G, Giorgi R.

Dipartimento di Studi Farmaceutici, Facolta di Farmacia, Universita degli Studi di Roma La Sapienza, Italy.

Interesting, n'est pas.—Preceding unsigned comment added by 81.104.26.110 (talk • contribs)

edited article

to what the refs say and to provide verifiable source links. You guys are quite a bit too optimistic and sensational, comparing that to morphine and methylphenidate. It is C IV for a reason, that means that the racemate has half of the analgetic effect of codeine according to refs, plus some stimulant effect. Also the analog mentioned has NO neurotoxic effect. You guys seem to have the reading understanding of healthy policemen. 70.137.142.102 (talk) 02:59, 25 September 2011 (UTC)[reply]