Talk:Co-stimulation

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Mechanism driving our co-stimulation

This article goes into great depth about the pharmacological protein signalling pathways that can promote or inhibit the immune response. However it never explains how this mechanism works in practice. I.e. an antigen binds and triggers an immune response, but to be very effective it requires co-stimulation. This article explains how these proteins and immunoglobulins enhance the immune response but not how or why they are created in the first place.

For example, you have some new novel viral infection. Your immune system recognises this invasive antigen and starts to respond, but co-stimulation is required for a full blown immune response. What is the process between initial recognition and regulated production of proteins stimulating the response?

This page just gives the biochemistry. Do the T cells both recognise the foreign antigen and produce the proteins that stimulate their own response? BeardedChimp (talk) 09:46, 5 July 2024 (UTC)[reply]