Talk:Chilblains
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merge
[edit]As noted on the proposed merge page, the Chillblains article misspells it, and they contradict each other (dry cold, cold in damp climates - I need someone to clarify).
In addition to merging, I would like to clean up the syntax. As I understand it, you use chilblain to refer to a particular sore, and chilblains as the condition wherein you have one or more of the chilblain sores. I will make this change unless challenged. Keyesc
trench foot
[edit]Chilblains and trench foot are not the same thing at all and I have removed the reference.
- Trench foot was un-named until World War One.[1]The war also produced similar or related names, such as trench back, trench fever, trench hand, trench leg (trench shin), trench lung, and trench nephritis. Trench mouth is a disease with a number of names, amongst which are Vincent's angina, Plaut's angina or ulcer, pseudomembranous angina, ulceromembranous angina, and phagedenic gingivitis. Both chilblain and frostbite differ from trench foot.
- Chilblain may occur in dry conditions.
- Frostbite is due to freezing of a part.
- Trench foot is associated with wet, unsanitary surroundings, coldness, and little movement by soldiers. It is more easily treated than frostbite. During WWI, British soldiers greatly reduced the occurrence of trench foot by changing their socks thrice daily, wearing boots of the proper size (not tight or ill-fitting), and the use of a foot powder. Foot hygiene was practiced as the chief preventive. Velocicaptor 12:45, 2 September 2006 (UTC)
connective tissue disorders
[edit]It could be mentioned that chilblains can be associated with connective tissue disorders.
- One could as easily proclaim a failure of the innate immune system, due to cold. It'd still end up OR, since there is zero research to prove either or anything else.Wzrd1 (talk) 05:41, 6 December 2012 (UTC)
Vitamin K?
[edit]The only thing I know by that name is ketamine. Like, the horse tranq. Since I can't see how that would help, is there another vitamin K or is this just wrong? —Preceding unsigned comment added by Sevenlies (talk • contribs) 00:09, 29 October 2007 (UTC)
- no, there is an actual vitamin found in some foods called vitamin k. I linked the text in the article to the vitamin k wikipedia page. anon. 04:37, 19 December 2007 (UTC) —Preceding unsigned comment added by 172.193.50.116 (talk)
- THAT is all bullshit on rye. Vitamin K is extremely well documented, indeed, it is an antidote to certain poisons! As in http://wiki.riteme.site/wiki/Vitamin_K .
NOT an element, not witch magic, not magic in general. Only a well documented vitamin that one would bleed to death without.Wzrd1 (talk) 05:44, 6 December 2012 (UTC)
Pippi Longstocking?
[edit]The reference to Pippi Longstocking should at least be explained. There is a Wilipedia article on Pippi Longstocking. I would make the link if I knew how. —Preceding unsigned comment added by 76.173.9.243 (talk) 09:39, 11 February 2009 (UTC)
how to die from it
[edit]The wiki article on Francois de Laval mentions that he died from chilblains on his heel. How would someone die from it? Was it common? What about today? --Richardson mcphillips (talk) 18:55, 30 April 2012 (UTC)
- Dead tissue causing infection in a pre-antibiotic era, which causes septicemia.Wzrd1 (talk) 05:39, 6 December 2012 (UTC)
Prevention
[edit]The URL for the article referenced in this section is correct, but when I followed it, it added "%7D" to the end got an 404 error as a result. I realize that the proper location for this is in the Reference section. I'm just mentioning this to help out whoever decides to undertake fixing up this article. — Preceding unsigned comment added by Ggurman (talk • contribs) 04:02, 27 April 2013 (UTC)
diagnostic challenges in US
[edit]- Am J Med. 2009 Dec;122(12):1152-5. doi: 10.1016/j.amjmed.2009.07.011. (ncbi.nlm.nih.gov/pubmed/19958897)
- Idiopathic chilblains.
- Prakash S1, Weisman MH.
- "Chilblains is a benign condition infrequently encountered in clinical practice; its resemblance to vasculitis or peripheral thromboemboli can often result in an extensive and unnecessary diagnostic work-up."
-71.174.175.150 (talk) 23:10, 28 January 2015 (UTC)
Contains contradiction
[edit]Should one keep the affected area dry or soak 3–4 times a day? This article recommends both but they appear contradictory. — Preceding unsigned comment added by 81.150.35.105 (talk) 08:52, 13 May 2016 (UTC)
- I have just discovered and deleted that segment, as it was unsourced and in the wrong category (Exposure instead of Treatment)Neuralnewt (talk) 01:14, 2 January 2018 (UTC)
Trimmed COVID-19 content based on primary sourcing
[edit]Trimmed [2] some COVID-related content that is not compliant with WP:MEDRS:
The occurrence of such lesions has been attributed to the similar interferon-1 mediated immune response in both COVID-19 and systemic lupus erythematosus, another possible explanation is based on a common genetic background.[1] In a recent genome-wide association study, the 3p21.31 region was found to be associated with COVID-19 severity.[2] This region also contains the TREX1 gene. Missense mutations of the TREX1 gene are responsible for familial chilblain lupus and its genetic polymorphisms have been implicated in the pathogenesis of systemic lupus erythematosus. The TREX1 mutation significantly reduces its exonucleolytic activity which results in the accumulation of nucleic acids that can stimulate type-I interferon responses and trigger autoimmunity. Thus an alteration in TREX1 activity, perhaps due to a promoter/enhancer modulation, may be responsible for the coincidence of both viral infection and an autoimmune phenomenon such as chilblain.[3]
...
According to Dr. Liji Thomas, MD studies: "None of the patients were positive for the virus on SARS-CoV-2 on RT-PCR of the nasopharyngeal swabs, or in the skin samples. Neither were the antibody tests positive for either IgM or IgG."[4]
References
- ^ Jabalameli, Navid (2021). "Overlap between Genetic Susceptibility to COVID-19 and Skin Diseases". Immunological Investigations: 1–8. doi:10.1080/08820139.2021.1876086. PMID 33494631.
- ^ Ellinghaus (2020). "Genomewide Association Study of Severe Covid-19 with Respiratory Failure". New England Journal of Medicine. 383 (16): 1522–1534. doi:10.1056/NEJMoa2020283. PMC 7315890. PMID 32558485.
- ^ Jabalameli (2021). "Overlap between Genetic Susceptibility to COVID-19 and Skin Diseases". Immunological Investigations: 1–8. doi:10.1080/08820139.2021.1876086. PMID 33494631.
- ^ News Medical, Life Sciences (26 July 2020). "Chilblains and COVID-19".
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