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Spectrin repeat containing nuclear envelope family member 3

From Wikipedia, the free encyclopedia
SYNE3
Identifiers
AliasesSYNE3, C14orf49, NET53, Nesp3, spectrin repeat containing nuclear envelope family member 3, C14orf139, KASH3, LINC00341, NCRNA00341
External IDsOMIM: 610861; MGI: 2442408; HomoloGene: 17625; GeneCards: SYNE3; OMA:SYNE3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042699
NM_172500

RefSeq (protein)

NP_689805
NP_001350621

NP_001036164
NP_766088
NP_001390387

Location (UCSC)Chr 14: 95.41 – 95.52 MbChr 12: 104.9 – 104.98 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Spectrin repeat containing nuclear envelope family member 3, or Nesprin-3, is a Nesprin-family protein that in humans is encoded by the SYNE3 gene.[5] Nesprin-3 localizes to the outer nuclear membrane, where it is retained by SUN domain-containing proteins. The n-terminus of Nesprin-3 faces the cytoplasm and associates with the cytolinker protein Plectin.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176438Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054150Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Spectrin repeat containing nuclear envelope family member 3". Retrieved 2018-05-27.
  6. ^ Wilhelmsen K, Litjens SH, Kuikman I, Tshimbalanga N, Janssen H, van den Bout I, et al. (December 2005). "Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin". The Journal of Cell Biology. 171 (5): 799–810. doi:10.1083/jcb.200506083. PMC 2171291. PMID 16330710.

Further reading

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