From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Spectrin repeat containing nuclear envelope family member 3 , or Nesprin-3, is a Nesprin -family protein that in humans is encoded by the SYNE3 gene .[ 5] Nesprin-3 localizes to the outer nuclear membrane, where it is retained by SUN domain -containing proteins. The n-terminus of Nesprin-3 faces the cytoplasm and associates with the cytolinker protein Plectin .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000176438 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054150 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: Spectrin repeat containing nuclear envelope family member 3" . Retrieved 2018-05-27 .
^ Wilhelmsen K, Litjens SH, Kuikman I, Tshimbalanga N, Janssen H, van den Bout I, et al. (December 2005). "Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin" . The Journal of Cell Biology . 171 (5): 799–810. doi :10.1083/jcb.200506083 . PMC 2171291 . PMID 16330710 .
Nery FC, Zeng J, Niland BP, Hewett J, Farley J, Irimia D, et al. (October 2008). "TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton" . Journal of Cell Science . 121 (Pt 20): 3476–3486. doi :10.1242/jcs.029454 . PMC 3539201 . PMID 18827015 .
Morgan JT, Pfeiffer ER, Thirkill TL, Kumar P, Peng G, Fridolfsson HN, et al. (November 2011). "Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization" . Molecular Biology of the Cell . 22 (22): 4324–4334. doi :10.1091/mbc.E11-04-0287 . PMC 3216658 . PMID 21937718 .
Liao M, Li B, Zhang S, Liu Q, Liao W, Xie W, Zhang Y (February 2017). "Relationship between LINC00341 expression and cancer prognosis" . Oncotarget . 8 (9): 15283–15293. doi :10.18632/oncotarget.14843 . PMC 5362486 . PMID 28146429 .