SonicParanoid

SonicParanoid is an algorithm for the de-novo prediction of orthologous genes among multiple species.^[1] It borrows the main idea from InParanoid^[2] with substantial changes to the algorithm that drastically reduce the time required for the analysis. Additionally, SonicParanoid generates groups of orthologous genes shared among the input proteomes using single-linkage hierarchical clustering or markov clustering.

References

^ Cosentino, Salvatore; Iwasaki, Wataru (2019). "SonicParanoid: fast, accurate and easy orthology inference". Bioinformatics. 35 (1): 149–151. doi:10.1093/bioinformatics/bty631. PMC 6298048. PMID 30032301.
^ Remm, Maido; Christian E.V. Storm; Erik L.L. Sonnhammer (2001). "Automatic clustering of orthologs and in-paralogs from pairwise species comparisons". Journal of Molecular Biology. 314 (5): 1041–1052. CiteSeerX 10.1.1.328.6724. doi:10.1006/jmbi.2000.5197. PMID 11743721.

External links

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[Cosentino2019-1] Cosentino, Salvatore; Iwasaki, Wataru (2019). "SonicParanoid: fast, accurate and easy orthology inference". Bioinformatics. 35 (1): 149–151. doi:10.1093/bioinformatics/bty631. PMC 6298048. PMID 30032301.

[Remm2001-2] Remm, Maido; Christian E.V. Storm; Erik L.L. Sonnhammer (2001). "Automatic clustering of orthologs and in-paralogs from pairwise species comparisons". Journal of Molecular Biology. 314 (5): 1041–1052. CiteSeerX 10.1.1.328.6724. doi:10.1006/jmbi.2000.5197. PMID 11743721.

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