Shc binding and spindle associated 1 like

SHCBP1L
Identifiers
Aliases	SHCBP1L, C1orf14, GE36, SHC binding and spindle associated 1 like
External IDs	MGI: 1919086; HomoloGene: 12800; GeneCards: SHCBP1L; OMA:SHCBP1L - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	182,953,525 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	153,328,320 bp
RNA expression pattern
	Top expressed in
	sperm; ; right testis; ; left testis; ; testicle; ; gastric mucosa; ; apex of heart; ; embryo; ; ventricular zone; ; ganglionic eminence; ; human musculoskeletal system;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; otolith organ; ; utricle; ; secondary oocyte; ; primary oocyte; ; zygote; ; Gonadal ridge; ; substantia nigra;
	More reference expression data
	n/a
Orthologs
	81626
	71836
	ENSG00000157060
	ENSMUSG00000042708
	Q9BZQ2
	Q3TTP0
	NM_030933; NM_001345928
	NM_001033162
	NP_001332857; NP_112195
	NP_001028334
	Wikidata
View/Edit Human	View/Edit Mouse

SHC binding and spindle associated 1 like is a protein that in humans is encoded by the SHCBP1L gene. ^[5]

Function

This gene encodes a Src homology 2 domain-binding protein 1-like protein. The encoded protein interacts with heat shock 70 kDa protein 2 and may be involved in maintaining spindle integrity during meiosis. This gene is located in region of chromoso0me 1 encompassing a prostate cancer susceptibility locus. [provided by RefSeq, Sep 2016].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000157060 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042708 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SHC binding and spindle associated 1 like". Retrieved 2018-06-26.

Function

References

Further reading