SYAP1

SYAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X3A
Identifiers
Aliases	SYAP1, PRO3113, synapse associated protein 1, BSTA
External IDs	MGI: 1914293; HomoloGene: 12078; GeneCards: SYAP1; OMA:SYAP1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	16,765,340 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	161,671,443 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; mucosa of ileum; ; jejunal mucosa; ; tibialis anterior muscle; ; myocardium of left ventricle; ; skin of arm; ; Skeletal muscle tissue of rectus abdominis; ; epithelium of nasopharynx; ; deltoid muscle; ; bronchial epithelial cell;
	Top expressed in
	white adipose tissue; ; Epithelium of choroid plexus; ; vestibular membrane of cochlear duct; ; brown adipose tissue; ; subcutaneous adipose tissue; ; transitional epithelium of urinary bladder; ; submandibular gland; ; pineal gland; ; calvaria; ; ovary;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi apparatus; nucleus; nucleoplasm; extracellular exosome; cytosol; cytoplasm; plasma membrane; membrane; cell junction; axon; dendrite; growth cone; extrinsic component of cytoplasmic side of plasma membrane; presynaptic membrane; cell projection; perikaryon; synapse; postsynaptic membrane; perinuclear region of cytoplasm;
Biological process	cell differentiation; cellular response to insulin stimulus; cellular response to platelet-derived growth factor stimulus; TORC2 signaling; positive regulation of fat cell differentiation; cellular response to epidermal growth factor stimulus; positive regulation of protein serine/threonine kinase activity; positive regulation of protein homodimerization activity; cellular response to insulin-like growth factor stimulus;
	Sources:Amigo / QuickGO
Orthologs
	94056
	67043
	ENSG00000169895
	ENSMUSG00000031357
	Q96A49
	Q9D5V6
	NM_032796
	NM_025932
	NP_116185
	NP_080208
	Wikidata
View/Edit Human	View/Edit Mouse

Synapse-associated protein 1 is a protein that in humans is encoded by the SYAP1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000169895 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031357 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (August 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Research. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
^ "Entrez Gene: SYAP1 synapse associated protein 1, SAP47 homolog (Drosophila)".

Yao Y, Suraokar M, Darnay BG, Hollier BG, Shaiken TE, Asano T, Chen CH, Chang BH, Lu Y, Mills GB, Sarbassov D, Mani SA, Abbruzzese JL, Reddy SA (January 2013). "BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation". Science Signaling. 6 (257): ra2. doi:10.1126/scisignal.2003295. PMC 3748614. PMID 23300339.
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Chang YC, Yu YL, Wang N, Xu YH (December 2001). "[Cloning and characterization of syap1, a down regulated gene in human hepatocellular carcinoma]". Shi Yan Sheng Wu Xue Bao. 34 (4): 319–22. PMID 12549212.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000169895 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031357 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11483580-5] Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (August 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Research. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.

[entrez-6] "Entrez Gene: SYAP1 synapse associated protein 1, SAP47 homolog (Drosophila)".

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References

Further reading